Cancer Epigenetics (eBook, PDF)

Redaktion: Tollefsbol, Trygve

• Format: PDF

Produktbeschreibung

The realization that heredity is not the sole determining factor in disease development recently sparked interest in the field of epigenetics, which is now the focus of many of the most exciting and significant advances in cancer research. This important and highly relevant text presents in-depth discussions of DNA methylation analysis and cancer, histone modifications and cancer, and other epigenetic aspects of cancer. It explores the role of epigenetics in the diagnosis, prognosis, and therapy of cancer and offers a comprehensive overview of current and potential new epigenetics advancements.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 472
• Erscheinungstermin: 19. September 2008
• Englisch
• ISBN-13: 9781420045802
• Artikelnr.: 42765891

Autorenporträt

Trygve Tollefsbol

Inhaltsangabe

The Role of Epigenetics in Cancer. DNA Hypomethylation in Cancer. DNA
Hypermethylation in Oncogenesis. Imprinting Alterations in Tumorigenesis.
Proteins that Modulate DNA Methylation Aberrations in Cancer. The Role of
DNA Methylation in Cancer Progression. Alterations in Histone Acetylation
in Tumorigenesis. Histone Methylation and the Initiation of Cancer. The
Role of Sirtuins in Aging and Tumorigenesis. Proteins that Alter Histone
Modifications in Cancer. Dietary and Environmental Influences on Histone
Modifications in Cancer. Noncoding RNAs in Cancer. Cancer-linked DNA Hyper-
and Hypomethylation: Chromosome Positional Effects. Chromatin Remodeling
and Cancer. Poly-ADP-ribosylation in Cancer. Polycomb Group Proteins in
Tumorigenesis. Cancer and Aging: The Epigenetic Connection. DNA Methylation
in Tumor Diagnosis. DNA Methylation Profiles as Prognostic Markers for
Cancer. Diagnosing Cancer Using Histone Modification Analysis. Histone
Modifications in Cancer Biology and Prognosis. Histone Deacetylase
Inhibitors in Cancer Therapy. Methylation Changes in Neoplasia: Diagnostic
and Therapeutic Implications. Clinical Trials and Approved Drugs for
Epigenetic Cancer Therapy. Future Directions in Epigenetic Cancer Research.