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Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa…mehr
Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol, many of which are neuroactive.
Summarizes cannabis and cannabinoid research in relation to neurological function
Contains chapter abstracts, key facts, a dictionary and a summary
Covers the neuroactivity of multiple Cannabis compounds beyond tetrahydrocannabinol
Includes conditions like depression, anxiety, Parkinson's, psychosis, and epilepsy
Discusses brain structure and brain development, including functional connectivity
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Inhaltsangabe
Preface I. Setting the scene and introductory chapters 1. Metabolomics of the cannabis plant Mickel Hiebert-Giesbrecht, Claudia Torres-Calzada and David Scott Wishart 2. The roots of Cannabis sativa: chemical and pharmacological profile L A. Rolim 3. Cannabis related compounds in beverages and food Ilaria Di Marco Pisciottano 4. The impact of prenatal cannabis exposure: an overview Natalia Kleinhans 5. Cannabis Genotoxicity and Cancer Incidence: Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse 6. Cannabis Genotoxicity and Cancer Incidence: A Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse 7. Cannabis, Cognitive impairment and Car Crash risk U.W. Preuss II. Cannabis usage 8. Recreational cannabis use: a French perspective of adverse effects Emilie Bouquet, Emilie Jouanjus and Maryse Lapeyre-Mestre 9. Acute and chronic impact of cannabis on human cognition Justin Matheson and Bernard Le Foll 10. Polydrug users, use of cannabidiol (CBD) and abuse potential/Polydrug users, use of cannabinoids and abuse potential Kerri Alexandra Schoedel 11. Cannabis stigmas: a narrative of features Matt Reid 12. Alterations of THC and CBD ratios and impact on cognition Erica Zamberletti 13. When cannabis is used for medicinal purposes: a focus on back pain R. L. Price III III. Pharmacological and Physiological Aspects 14. Cannabis, cannabinoids and receptor responses Yi Yang, Roya Derwish and Lakshmi P. Kotra 15. Cannabidiol (CBD): abuse potential and withdrawal Kenneth W. Sommerville and Beatrice Setnik 16. 4,5- Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications Malliga R. Iyer IV. Neurobiology of cannabis 17. Neurobiology of cannabis Rohit Goyal and Deepak Kumar 18. The kynurenine pathway, neurobiology and cannabis misuse: a new narrative Nuria Morales-Puerto and Esther O'Shea 19. Central nervous system cancers and use of cannabis and related products: an updated narrative J. Eduardo Rodriguez Almaraz and Nicholas Butowski 20. Chronic cannabis users: links with glutamate and resting state connectivity S.D. Newman 21. Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRI Thorsten Rudroff 22. Genetic Variation and Acute Responses to Cannabis Bernard Le Foll, Zoe Bourgault and Justin Matheson 23. Cell Signaling of the CB1 Cannabinoid Receptor via beta-arrestins, Cannabinoid Receptor Interacting Protein (CRIP1a) and other regulatory proteins Allyn C. Howlett 24. Cannabis and impact on memory: from in utero to adults Jennifer Willford, Meaghan Hazelet, Mohamad Khalaifa, Natacha DeGenna and Gale A. Richardson 25. Central CB1 receptors and age-related changes: investigating the effects of DELTA-9-tetrahydrocannabinol Brett C. Ginsburg and Hanana AlTfaili 26. Alcohol, cannabis and visual memory Concepcion Vinader-Caerols V. Neurobiology of cannabinoids 27. The role of Delta-FosB in the plasticity of the cannabinoid system Arturo Venebra-Munoz and Sara Mejía-Chávez 28. Functional profile of synthetic cannabinoid receptor agonists: exploring cannabinoid and non-cannabinoid targets Shivani Sachdev, Marina Santiago and Chris Bladen 29. Linking the G protein-coupled orphan receptor GPR55 to the cannabinoid receptors (CB1 and CB2): a new narrative Paula Morales, Raquel Guerrero-Alba and B.A. Marichal-Cancino 30. Proteomic analysis of cannabinoids in human oligodendrocytes Valéria Almeida 31. Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic system Rafael Rodriguez 32. Cannabidiol (The major non-psychotropic cannabinoid in the cannabis plant) and the PI3K/Akt pathway in the CNS Nadja Schroder 33. Effects of cannabidiol and other phytocannabinoids on ion channels Murat Oz, Keun-Hang Susan Yang, Mohamed Mahgoub, Georg Petroianu and Dietrich Lorke 34. Cannabis, neurodevelopment and the "two-hit hypothesis" Elisa Guma, Lani Cupo and Mallar Chakravarty VI. New and synthetic cannabinoids 35. Impact of tetrahydrocannabinol (THC ) and synthetic "spice"cannabinoids on nicotine use and abuse Christie Dawn Fowler and Angeline Dukes 36. Synthetic cannabinoids: how do they compare to DELTA9-tetrahydrocannabinol: neurological effects and beyond Chris S. Breivogel VII. Biomarkers, analysis and screening 37. The DSM-5 criteria of cannabis use disorder: methods and applications Mahadev Sen, Siddharth Sarkar and Yesh Singh 38. Cannabis and clinical high risk for psychosis: monitoring and smartphones Jean Addington VIII. Impact on non-neurological systems 39. The impact of cannabis and cannabinoids on the skin Jane M. Grant-Kels 40. Cannabis consumption in reproduction and teratogenicity Susana Sa and B.M. Fonseca 41. Cannabis compounds and putative cytotoxicity: profile of cancer cells Hadar Peeri and Hinanit Koltai IX. Treatments, strategies and resources 42. Motivational Interviewing for Cannabis Use Disorders: a narrative review from research to practice Hugo López-Pelayo, Maria Teresa Pons-Cabrera, Clara Oliveras Salvà and Pablo Rodrigo Guzmán Cortez 43. An Overview of Current Pharmacologic Interventions for Management of Cannabis Withdrawal and the Evidence for Their Use David Wolinsky 44. Managing cannabinoid hyperemesis syndrome in paediatrics: A new narrative review Justin P. Reinert 45. Gabapentinoids for the Treatment of Cannabis Use Disorder: A Focus on Human Laboratory Research Joshua A. Lile 46. Treating psychosis in users of synthetic cannabinoids T. Klimenko and Svetlana Shakhova X. Resources 47. Cannabis and Web based Resources Rajkumar Rajendram
Preface I. Setting the scene and introductory chapters 1. Metabolomics of the cannabis plant Mickel Hiebert-Giesbrecht, Claudia Torres-Calzada and David Scott Wishart 2. The roots of Cannabis sativa: chemical and pharmacological profile L A. Rolim 3. Cannabis related compounds in beverages and food Ilaria Di Marco Pisciottano 4. The impact of prenatal cannabis exposure: an overview Natalia Kleinhans 5. Cannabis Genotoxicity and Cancer Incidence: Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse 6. Cannabis Genotoxicity and Cancer Incidence: A Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse 7. Cannabis, Cognitive impairment and Car Crash risk U.W. Preuss II. Cannabis usage 8. Recreational cannabis use: a French perspective of adverse effects Emilie Bouquet, Emilie Jouanjus and Maryse Lapeyre-Mestre 9. Acute and chronic impact of cannabis on human cognition Justin Matheson and Bernard Le Foll 10. Polydrug users, use of cannabidiol (CBD) and abuse potential/Polydrug users, use of cannabinoids and abuse potential Kerri Alexandra Schoedel 11. Cannabis stigmas: a narrative of features Matt Reid 12. Alterations of THC and CBD ratios and impact on cognition Erica Zamberletti 13. When cannabis is used for medicinal purposes: a focus on back pain R. L. Price III III. Pharmacological and Physiological Aspects 14. Cannabis, cannabinoids and receptor responses Yi Yang, Roya Derwish and Lakshmi P. Kotra 15. Cannabidiol (CBD): abuse potential and withdrawal Kenneth W. Sommerville and Beatrice Setnik 16. 4,5- Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications Malliga R. Iyer IV. Neurobiology of cannabis 17. Neurobiology of cannabis Rohit Goyal and Deepak Kumar 18. The kynurenine pathway, neurobiology and cannabis misuse: a new narrative Nuria Morales-Puerto and Esther O'Shea 19. Central nervous system cancers and use of cannabis and related products: an updated narrative J. Eduardo Rodriguez Almaraz and Nicholas Butowski 20. Chronic cannabis users: links with glutamate and resting state connectivity S.D. Newman 21. Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRI Thorsten Rudroff 22. Genetic Variation and Acute Responses to Cannabis Bernard Le Foll, Zoe Bourgault and Justin Matheson 23. Cell Signaling of the CB1 Cannabinoid Receptor via beta-arrestins, Cannabinoid Receptor Interacting Protein (CRIP1a) and other regulatory proteins Allyn C. Howlett 24. Cannabis and impact on memory: from in utero to adults Jennifer Willford, Meaghan Hazelet, Mohamad Khalaifa, Natacha DeGenna and Gale A. Richardson 25. Central CB1 receptors and age-related changes: investigating the effects of DELTA-9-tetrahydrocannabinol Brett C. Ginsburg and Hanana AlTfaili 26. Alcohol, cannabis and visual memory Concepcion Vinader-Caerols V. Neurobiology of cannabinoids 27. The role of Delta-FosB in the plasticity of the cannabinoid system Arturo Venebra-Munoz and Sara Mejía-Chávez 28. Functional profile of synthetic cannabinoid receptor agonists: exploring cannabinoid and non-cannabinoid targets Shivani Sachdev, Marina Santiago and Chris Bladen 29. Linking the G protein-coupled orphan receptor GPR55 to the cannabinoid receptors (CB1 and CB2): a new narrative Paula Morales, Raquel Guerrero-Alba and B.A. Marichal-Cancino 30. Proteomic analysis of cannabinoids in human oligodendrocytes Valéria Almeida 31. Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic system Rafael Rodriguez 32. Cannabidiol (The major non-psychotropic cannabinoid in the cannabis plant) and the PI3K/Akt pathway in the CNS Nadja Schroder 33. Effects of cannabidiol and other phytocannabinoids on ion channels Murat Oz, Keun-Hang Susan Yang, Mohamed Mahgoub, Georg Petroianu and Dietrich Lorke 34. Cannabis, neurodevelopment and the "two-hit hypothesis" Elisa Guma, Lani Cupo and Mallar Chakravarty VI. New and synthetic cannabinoids 35. Impact of tetrahydrocannabinol (THC ) and synthetic "spice"cannabinoids on nicotine use and abuse Christie Dawn Fowler and Angeline Dukes 36. Synthetic cannabinoids: how do they compare to DELTA9-tetrahydrocannabinol: neurological effects and beyond Chris S. Breivogel VII. Biomarkers, analysis and screening 37. The DSM-5 criteria of cannabis use disorder: methods and applications Mahadev Sen, Siddharth Sarkar and Yesh Singh 38. Cannabis and clinical high risk for psychosis: monitoring and smartphones Jean Addington VIII. Impact on non-neurological systems 39. The impact of cannabis and cannabinoids on the skin Jane M. Grant-Kels 40. Cannabis consumption in reproduction and teratogenicity Susana Sa and B.M. Fonseca 41. Cannabis compounds and putative cytotoxicity: profile of cancer cells Hadar Peeri and Hinanit Koltai IX. Treatments, strategies and resources 42. Motivational Interviewing for Cannabis Use Disorders: a narrative review from research to practice Hugo López-Pelayo, Maria Teresa Pons-Cabrera, Clara Oliveras Salvà and Pablo Rodrigo Guzmán Cortez 43. An Overview of Current Pharmacologic Interventions for Management of Cannabis Withdrawal and the Evidence for Their Use David Wolinsky 44. Managing cannabinoid hyperemesis syndrome in paediatrics: A new narrative review Justin P. Reinert 45. Gabapentinoids for the Treatment of Cannabis Use Disorder: A Focus on Human Laboratory Research Joshua A. Lile 46. Treating psychosis in users of synthetic cannabinoids T. Klimenko and Svetlana Shakhova X. Resources 47. Cannabis and Web based Resources Rajkumar Rajendram
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