Cell-Cycle Mechanisms and Neuronal Cell Death (eBook, PDF)

• Format: PDF

Produktbeschreibung

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer’s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.

Produktdetails

• Verlag: Landes Bioscience / Springer US
• Erscheinungstermin: 6. März 2007
• Englisch
• ISBN-13: 9780387293905
• Artikelnr.: 37287118

Autorenporträt

Ferdinando Nicoletti, University of Rome "La Sapienza", Rome, Italy / Agata Copani, University of Catania, Catania, Italy

Inhaltsangabe

Cell Cycle Activation in Neurons.- Paved with Good Intentions.- The Role of Presenilins in the Cell Cycle and Apoptosis.- Cell Cycle Activation and Cell Death in the Nervous System.- Cell Cycle and Chromosome Segregation Defects in Alzheimer’s Disease.- Alzheimer Disease.- From Cell Cycle Activation to the Inhibition of the Wnt Pathway.

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Preface.- Cell Cycle Activation in Neurons: The Final Exit of Brain-Morpho-Dysregulation.- Paved with Good Intentions: The Link between Cell Cycle and Cell Death in the Mammalian Central Nervous System.- The Role of Presenilins in the Cell Cycle and Apoptosis.- Cell Cycle Activation and Cell Death in the Nervous System.- Cell Cycle and Chromosome Segregation: Defects in Alzheimer s Disease.- Alzheimer Disease: A New Beginning or a Final Exit?.- From Cell Cycle Activation to the Inhibition of the Wnt Pathway: A Hypothesis of How Neurons Die in Response to â-Amyloid.- Index.