Cellular Lipid in Health and Disease (eBook, ePUB)

Redaktion: Ntambi, James Mukasa

• Format: ePub

Produktbeschreibung

Cellular Lipid in Health and Disease presents a comprehensive and systematic coverage of the various roles lipids play in human biology.

This book is organized in four parts covering the foundational concepts of lipid biology all the way to the therapeutic opportunities they present. The first part is dedicated to the basic concepts of cellular lipid, the roles it plays in the cell, structure and physiology, regulation mechanisms, storage, and utilization. The second part is focused on lipid metabolism, covering the organelles involved in lipid trafficking, metabolism in aging, cholesterol homeostasis, lipid droplets (LDs), and lipid oxidation. Part three is dedicated to the roles lipids play in specific disease states including renal, metabolic, cardiovascular, and fatty liver diseases. Other conditions include cancer, neurodegenerative diseases, and the intricate relationship between cellular lipids and autophagy. The final part covers therapeutic opportunities, including drug carrier systems, modeling lipid metabolism, and prevention therapeutics.

Cellular Lipid in Health and Disease is a complete reference targeted at graduate students and early career researchers in cell biology, biochemistry, and pharmacology. Research physicians can also benefit from the foundational content and links to pathologies and therapeutic opportunities.

• Offers a complete and systematic coverage of lipid biology
• Provides foundational content and establishes the needed connections to translational aspects of the research in this area
• Includes chapters on the therapeutic opportunities presented by lipids

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 450
• Erscheinungstermin: 21. August 2023
• Englisch
• ISBN-13: 9780323955836
• Artikelnr.: 68684814

Inhaltsangabe

1 Structure and function of mammalian sphingolipids in health and disease
Mariona Rabionet, Robert Engel and Roger Sandhoff
2 Intracellular lipid storage and utilization in adipocytes
Vishva M. Sharma, James M. Ntambi and Vishwajeet Puri
3 Metabolic control by lipid droplet proteins
Dilip Menon, Rakesh Mohan Jha, Arpita Nahak and Sheetal Gandotra
4 From endoplasmic reticulum to nucleus: the fate of cellular fatty acids
Antoine Jutras-Carignan, Tania Guillemette and Catherine Mounier
5 Lipid trafficking and signaling in adipocytes
Yan Tang and Qi-Qun Tang
6 Cell and molecular basis for maintenance of cholesterol homeostasis
Townsend A. Smith and Russell A. DeBose-Boyd
7 Interplay between phospholipid signaling and autophagy
Meenu Maan and Mainak Dutta
8 The role of cellular lipid metabolism in aging
Xiaoli Chen and Jun Liu
9 Plasma lipid trafficking in type 2 diabetes
Isabella James, Gina Wade, Helaina Von Bank, Ayren McGahee, Autumn
Chevalier, Paula Gonzalez, Kayla Bote, James M. Ntambi and Judith Simcox
10 Lipotoxicity in the pathogenesis of chronic kidney disease complications
Masashi Masuda, Yuji Shiozaki and Makoto Miyazaki
11 Cellular lipids in the molecular pathogenesis of obesity
Mashudu G. Matumba, Ademola O. Ayeleso, James M. Ntambi and Emmanuel
Mukwevho
12 Effects of cellular lipids on heart in pathology and physiology
Volodymyr V. Balatskyi, Marcin Wolosiewicz, Aneta M. Dobosz, Zuzanna
Tracz-Gaszewska, Adrian Sowka, Maria Kendziorek, Ewelina Krogulec, Viktor
O. Navrulin and Pawel Dobrzyn
13 Uncoupling of fat deposition and inflammation during nonalcoholic fatty
liver disease
Honggui Li, Xinlei Guo, Eduardo Aquino and Chaodong Wu
14 Cellular lipids and colorectal cancer
Seong-Ho Lee and Joseph LoBianco
15 Lipid metabolism in neurodegenerative diseases
Jeroen F.J. Bogie, Jeroen Guns and Sam Vanherle
16 Cellular lipids in B cell immunity, inflammation, and cancer
Yana Zhang, James M. Ntambi and Deyu Fang
17 Role of cellular fatty acids in combating the corona virus
Abhishek Saxena and Archana Tiwari
18 Cellular lipids and viral infection
Z. Zhang, C. Baguley, X. Wang and B. Kopek
19 Acetyl-CoA and acetylation in biology and disease
Luigi Puglielli, Michael J. Rigby and Gonzalo Fernandez-Fuente
20 Role of omega-3 and -6 fatty acids in the inflammatory processes of
obesity, hypertension, and autoimmunity
F. Enrique Gömez, Martha Kaufer-Horwitz, He¿ctor Bourges and Gabriela E.
Mancera-Chavez