Cellular Peptidases in Immune Functions and Diseases (eBook, PDF)
Redaktion: Ansorge, Siegfried; Langner, Jürgen
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Cellular Peptidases in Immune Functions and Diseases (eBook, PDF)
Redaktion: Ansorge, Siegfried; Langner, Jürgen
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Proceedings of an international conference held in Magdeburg, Germany, November 3-5, 1996
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- Größe: 35.52MB
Proceedings of an international conference held in Magdeburg, Germany, November 3-5, 1996
Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Springer US
- Seitenzahl: 338
- Erscheinungstermin: 29. Juni 2013
- Englisch
- ISBN-13: 9781475796131
- Artikelnr.: 43988375
- Verlag: Springer US
- Seitenzahl: 338
- Erscheinungstermin: 29. Juni 2013
- Englisch
- ISBN-13: 9781475796131
- Artikelnr.: 43988375
- Herstellerkennzeichnung Die Herstellerinformationen sind derzeit nicht verfügbar.
I: Membrane Peptidases in Immune Functions and Inflammation.- 1. Membrane Metalloendopeptidases in Immune Function and Disease.- 2. Structural Studies of Aminopeptidase P: A Novel Cellular Peptidase.- 3. Aminopeptidase P: A Cell-Surface Antigen of Endothelial and Lymphoid Cells.- 4. Human Lymphocyte X-Prolyl Aminopeptidase (Aminopeptidase P)-like Protein: A New Member of the Proline Peptidase Family?.- 5. Specific Inhibitors of Aminopeptidase P: Peptides and Pseudopeptides of 2-Hydroxy-3-Amino Acids.- 6. ?-Glutamyl Transpeptidase, a Blood-Brain Barrier Associated Membrane Protein: Splitting Peptides to Transport Amino Acids.- 7. Structure and Expression of Aminopeptidase N.- 8. Activation-Dependent Induction of T Cell Alanyl Aminopeptidase and Its Possible Involvement in T Cell Growth.- 9. Antisense-Mediated Inhibition of Aminopeptidase N (CD13) Markedly Decreases Growth Rates of Hematopoietic Tumour Cells.- 10. Co-Incubation of Lymphocytes with Fibroblast-like Synoviocytes and Other Cell Types Can Induce Lymphocytic Surface Expression of Aminopeptidase N/CD13.- 11. Two Transfected Endothelial Cell Lines Expressing High Levels of Membrane Bound or Soluble Aminopeptidase N.- 12. Aminopeptidase N-Mediated Signal Transduction and Inhibition of Proliferation of Human Myeloid Cells.- 13. Regulation of Thymic Development by Neprilysin Inhibition.- 14. Proteases of Isolated Pancreatic Acinar Cells after Caerulein Hyperstimulation.- II: CD26/Dipeptidylpeptidase IV on Lymphocytes.- 15. Structure of CD26 (Dipeptidyl Peptidase IV) and Function in Human T Cell Activation.- 16. Molecular Associations Required for Signalling via Dipeptidyl Peptidase IV (CD26).- 17. CD26/Dipeptidyl Peptidase IV in Lymphocyte Growth Regulation.- 18. CD26 Is Involved in Regulation of CytokineProduction in Natural Killer Cells.- 19. The Effect of Anti-CD26 Antibodies on DNA Synthesis and Cytokine Production (IL-2, IL-10 and IFN-?) Depends on Enzymatic Activity of DP IV/CD26.- 20. New Fluorogenic Dipeptidyl Peptidase IV/CD26 Substrates and Inhibitors.- 21. Molecular Analyses of Human and Rat Dipeptidyl Peptidase IV.- 22. A Molecular Model of the Active Site of Dipeptidyl Peptidase IV: Explanation of the Substrate Specificity and Interaction with Inhibitors.- 23. The Level of CD26 Determines the Rate of HIV Entry in a CD4+ T-Cell Line.- 24. HIV-1 Envelope gp 120 and Viral Particles Block Adenosine Deaminase Binding to Human CD26.- 25. Further Characterization of DPP IV-?, a Novel Cell Surface Expressed Protein with Dipeptidyl Peptidase Activity.- 26. Expression of Dipeptidylpeptidase IV (DPP IV/CD26) Activity on Human Myeloid and B Lineage Cells, and Cell Growth Suppression by the Inhibition of DPP IV Activity.- 27. CD26 as a Positive Regulator of HIV Envelope-Glycoprotein Induced Apoptosis in CD4+ T Cells.- 28. Comparative Study of CD26 as a Thl-like and CD30 as a Potential Th2-like Operational Marker in Leprosy.- III: Peptidases Involved in Cytokine Actions and in the Pathogenesis of Disease.- 29. Regulation of Neutrophil Activation by Proteolytic Processing of Platelet-Derived a-Chemokines.- 30. Selective Proteolytical Cleavage of the Ligand-Binding Chains of the IL-2-Receptor and IL-6-Receptor by Neutrophil-Derived Proteases.- 31. In Vitro Effects of ?-Glutamyltranspeptidase Inhibitor Acivicin on Human Myeloid and B Lineage Cells.- 32. Expression of Several Matrix Metalloproteinase Genes in Human Monocytic Cells.- 33. Lysosomal Cysteine Peptidases and Malignant Tumours.- 34. Expression of Cysteine Protease Inhibitors Stefin A, Stefin B, and Cystatin Cin Human Lung Tumor Tissue.- 35. Contribution of the Proteasome to the a-Secretase Pathway in Alzheimer's Disease.- 36. Dipeptidyl Peptidase IV (CD26) and Alzheimer Amyloid Protein Precursor (APP) in Polymyositìs.- 37, The HIV Protease and Therapies for AIDS.- 38. Leukodiapedesis, Function, and Physiological Role of Leucocyte Matrix Metalloproteinases.- 39. Matrix Metalloproteinases in Experimental Autoimmune Encephalomyelitis.- 40. Interaction of Transforming Growth Factor ß (TGFß) with Proteinase 3.- 41. Liver Cysteine Proteinases in Macrophage Depression Induced by Gadolinium Chloride.- Contributors.
I: Membrane Peptidases in Immune Functions and Inflammation.- 1. Membrane Metalloendopeptidases in Immune Function and Disease.- 2. Structural Studies of Aminopeptidase P: A Novel Cellular Peptidase.- 3. Aminopeptidase P: A Cell-Surface Antigen of Endothelial and Lymphoid Cells.- 4. Human Lymphocyte X-Prolyl Aminopeptidase (Aminopeptidase P)-like Protein: A New Member of the Proline Peptidase Family?.- 5. Specific Inhibitors of Aminopeptidase P: Peptides and Pseudopeptides of 2-Hydroxy-3-Amino Acids.- 6. ?-Glutamyl Transpeptidase, a Blood-Brain Barrier Associated Membrane Protein: Splitting Peptides to Transport Amino Acids.- 7. Structure and Expression of Aminopeptidase N.- 8. Activation-Dependent Induction of T Cell Alanyl Aminopeptidase and Its Possible Involvement in T Cell Growth.- 9. Antisense-Mediated Inhibition of Aminopeptidase N (CD13) Markedly Decreases Growth Rates of Hematopoietic Tumour Cells.- 10. Co-Incubation of Lymphocytes with Fibroblast-like Synoviocytes and Other Cell Types Can Induce Lymphocytic Surface Expression of Aminopeptidase N/CD13.- 11. Two Transfected Endothelial Cell Lines Expressing High Levels of Membrane Bound or Soluble Aminopeptidase N.- 12. Aminopeptidase N-Mediated Signal Transduction and Inhibition of Proliferation of Human Myeloid Cells.- 13. Regulation of Thymic Development by Neprilysin Inhibition.- 14. Proteases of Isolated Pancreatic Acinar Cells after Caerulein Hyperstimulation.- II: CD26/Dipeptidylpeptidase IV on Lymphocytes.- 15. Structure of CD26 (Dipeptidyl Peptidase IV) and Function in Human T Cell Activation.- 16. Molecular Associations Required for Signalling via Dipeptidyl Peptidase IV (CD26).- 17. CD26/Dipeptidyl Peptidase IV in Lymphocyte Growth Regulation.- 18. CD26 Is Involved in Regulation of CytokineProduction in Natural Killer Cells.- 19. The Effect of Anti-CD26 Antibodies on DNA Synthesis and Cytokine Production (IL-2, IL-10 and IFN-?) Depends on Enzymatic Activity of DP IV/CD26.- 20. New Fluorogenic Dipeptidyl Peptidase IV/CD26 Substrates and Inhibitors.- 21. Molecular Analyses of Human and Rat Dipeptidyl Peptidase IV.- 22. A Molecular Model of the Active Site of Dipeptidyl Peptidase IV: Explanation of the Substrate Specificity and Interaction with Inhibitors.- 23. The Level of CD26 Determines the Rate of HIV Entry in a CD4+ T-Cell Line.- 24. HIV-1 Envelope gp 120 and Viral Particles Block Adenosine Deaminase Binding to Human CD26.- 25. Further Characterization of DPP IV-?, a Novel Cell Surface Expressed Protein with Dipeptidyl Peptidase Activity.- 26. Expression of Dipeptidylpeptidase IV (DPP IV/CD26) Activity on Human Myeloid and B Lineage Cells, and Cell Growth Suppression by the Inhibition of DPP IV Activity.- 27. CD26 as a Positive Regulator of HIV Envelope-Glycoprotein Induced Apoptosis in CD4+ T Cells.- 28. Comparative Study of CD26 as a Thl-like and CD30 as a Potential Th2-like Operational Marker in Leprosy.- III: Peptidases Involved in Cytokine Actions and in the Pathogenesis of Disease.- 29. Regulation of Neutrophil Activation by Proteolytic Processing of Platelet-Derived a-Chemokines.- 30. Selective Proteolytical Cleavage of the Ligand-Binding Chains of the IL-2-Receptor and IL-6-Receptor by Neutrophil-Derived Proteases.- 31. In Vitro Effects of ?-Glutamyltranspeptidase Inhibitor Acivicin on Human Myeloid and B Lineage Cells.- 32. Expression of Several Matrix Metalloproteinase Genes in Human Monocytic Cells.- 33. Lysosomal Cysteine Peptidases and Malignant Tumours.- 34. Expression of Cysteine Protease Inhibitors Stefin A, Stefin B, and Cystatin Cin Human Lung Tumor Tissue.- 35. Contribution of the Proteasome to the a-Secretase Pathway in Alzheimer's Disease.- 36. Dipeptidyl Peptidase IV (CD26) and Alzheimer Amyloid Protein Precursor (APP) in Polymyositìs.- 37, The HIV Protease and Therapies for AIDS.- 38. Leukodiapedesis, Function, and Physiological Role of Leucocyte Matrix Metalloproteinases.- 39. Matrix Metalloproteinases in Experimental Autoimmune Encephalomyelitis.- 40. Interaction of Transforming Growth Factor ß (TGFß) with Proteinase 3.- 41. Liver Cysteine Proteinases in Macrophage Depression Induced by Gadolinium Chloride.- Contributors.