Central Nervous System Diseases and Inflammation (eBook, PDF)

Redaktion: Lane, Thomas E.; Wyss-Coray, Tony; Bergmann, Conni; Carson, Monica

• Format: PDF

Produktbeschreibung

This volume serves as a succinct and well-organized reference volume focused on inflammatory CNS disease to a wide audience. The text is comprised of four sections revolving around current areas of interest in the fields of neuroimmunology, virology, pharmacology and disease. Sections of this text focus on a specific category of diseases as well as the pharmacological, virological, and immunological effects of and on the disease.

Although many have covered this topic, few have provided a volume as concise and efficient. Each disease is broken down on a variety of scientific levels without getting into the history of the disease. This approach provides a succinct overview of a specific subject encompassing interrelated topics pertaining to neurology, immunology and disease. The information provided in Central Nervous System Diseases and Inflammation will be useful for researchers, clinicians, as well as a valuable resource for students interested in the fascinating arena of neuroinflammation.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 318
• Erscheinungstermin: 24. Dezember 2007
• Englisch
• ISBN-13: 9780387738949
• Artikelnr.: 37288022

Inhaltsangabe

Section I - Microglia and CNS Disease.- 1. Microglia: a CNS-Specific Tissue Macrophage.- Shweta S. Puntambekar, Jonathan M. Doose, Monica J Carson.- 2. Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments.- S. A. Austin and C. K. Combs.- 3. Pericytes.- Martin Krüger and Ingo Bechmann.- 4. Imaging Microglia in the Central Nervous System: Past, Present, and Future.- Dimitrios Davalos and Katerina Akassoglou.- Section II - Innate Immune Responses within the Brain.- 5. Cytokines in CNS inflammation and disease.- Malú G. Tansey and Tony Wyss-Coray.- 6. Arachidonic acid metabolites: Function in neurotoxicity and inflammation in the central nervous system.- and T.J. Montine.- 7. Pattern Recognition Receptors in CNS Disease.- Pamela A. Carpentier, D'Anne S. Duncan, Stephen D. Miller.- 8. The Complement System in the CNS: Thinking again.- Andrea J. Tenner and Karntipa Pisalyaput.- Section III - Chemokines and CNS Disease.- 9. Chemokines and autoimmune demyelination.- Michaela Fux, Jason Millward, and Trevor Owens.- 10. Chemokine actions in the CNS: Insights from transgenic models.- Marcus Müller and Iain L. Campbell.- 11. Chemokines and Spinal Cord Injury.- Maya N. Hatch and Hans S. Keirstead.- 12. The Usual Suspects: Chemokines and Microbial Infection of the Central Nervous System.- Michelle J. Hickey, Linda N. Stiles, Chris S. Schaumburg, and Thomas E. Lane.- Section IV - Antigen Presentation and Immune Responses within the Brain.- 13. CNS Dendritic Cells in Inflammation and Disease.- Samantha L. Bailey and Stephen D. Miller.- 14. MHC class I Expression and CD8+ T Cell Function: Towards the Cell Biology of T-APC Interactions in the Infected Brain.- Cornelia Bergmann and Pedro Lowenstein.

Rezensionen

From the reviews: "The involvement of the immune system in central nervous system diseases is highlighted in this book, which details important advances in the understanding of certain aspects of neuroinflammation. ... This is clearly appropriate for clinicians and researchers who are interested in neuroinflammation in the central nervous system. It also can be a valuable research guide for students who are interested in learning some basics on this topic. ... It makes worthwhile contributions to this area." (Christine Maria Rohowsky-Kochan, Doody's Review Service, September, 2008)