Christopher T Walsh, Yi Tang

Chemical Biology of Human Vitamins (eBook, ePUB)

• Format: ePub

Produktbeschreibung

As humans evolved from primordial organisms they lost the capacity to make certain essential molecules. By their very absence in specific pathologies and diseases, the thirteen human vitamins were discovered and their crucial role in metabolism revealed.

This textbook provides a thorough chemocentric view on the key small molecules of life, the human vitamins and their active coenzyme forms. Detailing how their unique chemistries control the interconversion and the flux of hundreds of central human metabolites, The Chemical Biology of Human Vitamins examines the parallel and convergent tracks of the vitamins and their coenzyme forms. Analysing the mode of action of each of the vitamins, the book will illuminate the challenges that face each cell; metabolism could not proceed without the chemical functional groups vitamins provide.

Authored by leading educators, this text will serve as an ideal guide and reference point for chemists in both academia and industry, graduates and advanced undergraduate students in biochemistry, chemical biology, metabolism and metabolomics.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, D ausgeliefert werden.

Produktdetails

• Verlag: RSC
• Seitenzahl: 446
• Erscheinungstermin: 5. Oktober 2018
• Englisch
• ISBN-13: 9781788015424
• Artikelnr.: 56835944

Autorenporträt

Prof Walsh was on the faculty of MIT and Harvard Medical School and is now affiliated with the ChEM-H Institute at Stanford University. Yi Tang is a professor of Chemical and Biochemical Engineering, and Chemistry at UCLA. Between them they have published many research and review articles that examine the chemical logic that underlies both primary and secondary metabolic pathways. Among their joint efforts is the recent monograph Natural Product Biosynthesis, Chemical Logic and Enzymatic Machinery (Royal Society of Chemistry, 2017).

Inhaltsangabe

Section 1: Overview, A Molecular View of Vitamin Action
Human Vitamins: Discovery and Characterization
Metabolic Logic through the Lens of Coenzyme Forms of Human Vitamins
Section 2: The Metabolic Roles of Water-soluble Vitamins
Vitamin B1 Converted to the Coenzyme Thiamin Pyrophosphate
Vitamin B2 Riboflavin
Vitamin B3 Niacin and the Nicotinamide Coenzymes
Vitamin B5: Pantothenate
Coenzyme Forms of Vitamin B6
Vitamin B7: Biotin
Vitamin B9: Folic Acid
Vitamin B12: Two Coenzyme Forms
Vitamin C: Ascorbic Acid
Section 3: The Metabolic Roles of Lipid-soluble Vitamins
Vitamin A: Three Vitamer Forms: Retinol, Retinal, and Retinoic Acid
Vitamin D
Vitamin E
Vitamin K
Section 4
Vitamin Chemistry Drives Human Metabolic Logic
Subject Index