Daniel A. Beard

Chemical Biophysics (eBook, PDF)

Quantitative Analysis of Cellular Systems

• Format: PDF

Produktbeschreibung

Chemical Biophysics provides an engineering-based approach to biochemical system analysis for graduate-level courses on systems biology, computational bioengineering and molecular biophysics. It is the first textbook to apply rigorous physical chemistry principles to mathematical and computational modeling of biochemical systems for an interdisciplinary audience. The book is structured to show the student the basic biophysical concepts before applying this theory to computational modeling and analysis, building up to advanced topics and research. Topics explored include the kinetics of nonequilibrium open biological systems, enzyme mediated reactions, metabolic networks, biological transport processes, large-scale biochemical networks and stochastic processes in biochemical systems. End-of-chapter exercises range from confidence-building calculations to computational simulation projects.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 29. Mai 2008
• Englisch
• ISBN-13: 9780511401275
• Artikelnr.: 38206560

Autorenporträt

Daniel A. Beard is Associate Professor in the Department of Physiology, Biotechnology and Bioengineering Center, Medical College of Wisconsin. He researches nonequilibrium thermodynamics in biochemical networks.
Hong Qian is Professor of Applied Mathematics in the University of Washington. His research interests span computational systems biology, molecular biophysics and mathematical biology and include stochastic analysis and statistical physics of biological systems.

Inhaltsangabe

Preface
Introduction
Part I. Background Material: 1. Concepts from physical chemistry
2. Conventions and calculations for biochemical systems
3. Chemical kinetics and transport processes
Part II. Analysis and Modeling of Biochemical Systems: 4. Enzyme-catalyzed reactions
5. Biochemical signaling modules
6. Biochemical reaction networks
7. Coupled biochemical systems and membrane transport
Part III. Special Topics: 8. Spatially distributed systems and reaction-diffusion modeling
9. Constraint-based analysis of biochemical systems
10. Biomacromolecular structure and molecular association
11. Stochastic biochemical systems and the chemical master equation
12. Appendix: the statistical basis of thermodynamics
Bibliography
Index.