Lesley A. Colby, Megan H. Nowland, Lucy H. Kennedy

Clinical Laboratory Animal Medicine (eBook, ePUB)

An Introduction

• Format: ePub

Produktbeschreibung

The revised fifth edition of Clinical Laboratory Animal Medicine: An Introduction is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals. The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and genetic editing, and expanded coverage of environmental enrichment and pain management. The book presents helpful tip boxes, images, and review questions to aid in comprehension and learning, and a companion website provides editable review questions and answers, instructional PowerPoints, and additional images not found in the book. This important text: * Provides a complete introduction to laboratory animal husbandry, diseases, and treatments * Offers a user-friendly format with helpful content that highlights important concepts * Contains new knowledge relating to technical methodologies, diseases, drug dosages, laws and regulations, and organizations * Covers information on regulations, facilities, equipment, housing, and research variables as well as veterinary care * Includes new chapters on zebrafish and cattle, sheep, goats, and pigs Written for veterinary technicians, veterinary students, practicing veterinarians, and research scientists, the fifth edition of Clinical Laboratory Animal Medicine continues to offer an essential guide to the ethical treatment and anatomic and physiological characteristics of research animals.

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Produktdetails

• Verlag: Jossey-Bass
• Seitenzahl: 512
• Erscheinungstermin: 11. Oktober 2019
• Englisch
• ISBN-13: 9781119489597
• Artikelnr.: 58045357

Autorenporträt

The authors Lesley A. Colby, DVM, MS, DACLAM, is an Associate Professor and Senior Director of Animal Resources and Operations in the Department of Comparative Medicine at the University of Washington in Seattle, Washington, USA. Megan H. Nowland, DVM, DACLAM, is an Associate Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA. Lucy H. Kennedy, DVM, DACLAM, is an Assistant Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA.

Inhaltsangabe

About the Authors xii

Preface xiii

About the Companion Website xiv

1 Introduction to Laboratory Animal Medicine 1

Animals Used in Research, Teaching, and Testing 2

Ethical Considerations 8

Organizations 12

Bibliography 17

Further Reading 18

Chapter 1 Review 19

2 Regulations, Policies, and Principles Governing the Care and Use of Laboratory Animals 22

Animal Welfare Act and Regulations 22

Public Health Service Policy on Humane Care and Use of Laboratory Animals 28

Other Regulations, Policies, Guidance Documents, and Organizations 31

References 36

Further Reading 37

Chapter 2 Review 37

3 Facility Design, Housing, Equipment, and Management 39

Laboratory Animal Facility Design 39

Common Facility Classifications 46

Housing 50

Facility Equipment 59

Management 66

Bibliography 69

Further Reading 69

Chapter 3 Review 71

4 Mice 74

Genetics 74

Microbiologic Classifications 76

Uses 77

Behavior 77

Anatomic and Physiologic Features 78

Breeding and Reproduction 80

Husbandry 81

Techniques 86

Special Techniques: Transgenic Production Technology 96

Therapeutic Agents 101

Introduction to Diseases of Mice 101

Viral Diseases 107

References 114

Further Reading 119

Chapter 4 Review 122

5 Rats 124

Genetics 124

Microbiologic Classifications 125

Uses 126

Behavior 126

Anatomic and Physiologic Features 127

Breeding and Reproduction 129

Husbandry 130

Techniques 133

Therapeutic Agents 143

Introduction to Diseases of Rats 144

Bibliography 157

Further Reading 162

Chapter 5 Review 162

6 Gerbils 165

Uses 165

Behavior 166

Anatomic and Physiologic Features 166

Breeding and Reproduction 167

Husbandry 168

Techniques 170

Therapeutic Agents 176

Introduction to Diseases of Gerbils 176

Bibliography 181

Further Reading 183

Chapter 6 Review 184

7 Hamsters 185

Uses 185

Behavior 186

Anatomic and Physiologic Features 187

Breeding and Reproduction 189

Husbandry 190

Techniques 192

Therapeutic Agents 198

Introduction to Diseases of Hamsters 198

Bibliography 207

Further Reading 209

Chapter 7 Review 210

8 Guinea Pigs 212

Uses 212

Behavior 213

Anatomic and Physiologic Features 214

Breeding and Reproduction 216

Husbandry 218

Techniques 219

Therapeutic Agents 225

Introduction to Diseases of Guinea Pigs 226

Bibliography 238

Further Reading 240

Chapter 8 Review 242

9 Chinchillas 243

Uses 243

Behavior 244

Anatomic and Physiologic Features 244

Breeding and Reproduction 246

Husbandry 247

Techniques 249

Therapeutic Agents 253

Introduction to Diseases of Chinchillas 255

Bibliography 260

Further Reading 262

Chapter 9 Review 262

10 Zebrafish 264

Uses 264

Behavior 265

Anatomic and Physiologic Features 265

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