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Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and…mehr
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world's leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.
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Autorenporträt
About the editor Prof. J. Enrique Domínguez-Muñoz graduated in medicine from the University of Alcalá de Henares in Madrid, and got his PhD at the same University in 1990. In 1998, he became Director of the Department of Gastroenterology and Hepatology at the University Hospital of Santiago de Compostela, Spain. He is also Professor of Medicine at the University of Santiago de Compostela and permanent member of the Royal Academy of Medicine of Galicia. He has published more than 300 papers in peer reviewed journals, and has edited 12 books. He has been elected President of the European Pancreatic Club for 2024.
Inhaltsangabe
Contributors xxxiii
Foreword xlvi
Preface xlvii
Dedication xlviii
Section I Acute Pancreatitis 1
1 Acute Pancreatitis: An Overview 3 Jodie A. Barkin and Jamie S. Barkin
2 How to Deal with the Etiological Diagnosis of Acute Pancreatitis in Clinical Practice? 17 Soumya Jagannath and Pramod Kumar Garg
3 Definition of Complications and Severity of Acute Pancreatitis for Clinical Practice 25 David X. Jin, Peter A. Banks, and Julia McNabb-Baltar
4 Early Prediction of Severity in Acute Pancreatitis: What can be Done in Clinical Practice? 31 Peter J. Lee and Georgios I. Papachristou
5 Role of CT Scan in Acute Pancreatitis: When is it Indicated and What Information can be Obtained? 40 Elham Afghani, Mahya Faghih, and Vikesh K. Singh
6 Role of MRI in Acute Pancreatitis: When is it Indicated and What Information can be Obtained? 47 Fatih Akisik
7 Treatment of Acute Pancreatitis in The Emergency Room: What Should be Done During the First Hours of Disease? 53 Thiruvengadam Muniraj and Santhi Swaroop Vege
8 Acute Pancreatitis: A Practical Guideline for the Monitoring and Treatment of Systemic Complications 59 Enrique de Madaria and Felix Zubia-Olaskoaga
9 Guidelines for the Treatment of Pain in Acute Pancreatitis 66 László Czakó
10 Nutrition in the Acute Phase of Pancreatitis: Why, When, How and How Long? 72 Angela Pham and Chris E. Forsmark
11 Oral Refeeding in Acute Pancreatitis: When and How Should it be Restarted? 78 José Lariño-Noia and Daniel de la Iglesia-García
12 Pharmacological Therapy for Acute Pancreatitis: Any Light at the End of the Tunnel? 83 Rajarshi Mukherjee, Muhammad Awais, Wenhao Cai, Wei Huang, Peter Szatmary, and Robert Sutton
13 Indication and Optimal Timing of ERCP in Acute Pancreatitis 95 Theodor Voiosu, Ivo Boskoski, and Guido Costamagna
14 How to Deal with Infected Pancreatic Necrosis? 100 J. Enrique Domínguez-Muñoz
15 Minimally Invasive Surgical Necrosectomy in Clinical Practice: Indications, Technical Issues, and Optimal Timing 105 Patricia Sánchez-Velázquez, Fernando Burdío, and Ignasi Povesi
16 Endoscopic Necrosectomy in Clinical Practice: Indications, Technical Issues and Optimal Timing 113 Jodie A. Barkin and Andres Gelrud
17 Management of Acute Pancreatic Pseudocyst: When to Observe, When and How to Drain? 120 Muhammad F. Dawwas and Kofi W. Oppong
18 The Disconnected Main Pancreatic Duct Syndrome: How to Proceed in Clinical Practice? 126 Mario Peláez-Luna, Andrea Soriano-Ríos, and Luis Uscanga-Dominguez
19 Vasculature Complications in Pancreatitis: How to Deal with Them? 132 Daniel G. McCall and Timothy B. Gardner
20 Acute Relapsing Pancreatitis: What can be Done to Prevent Relapses? 141 Jorge D. Machicado and Dhiraj Yadav
21 Diagnosis and Therapeutic Approach to Pancreatic Exocrine Insufficiency after Acute Pancreatitis 151 Hester C. Timmerhuis, Christa J. Sperna Weiland, and Hjalmar C. van Santvoort
22 Asymptomatic Chronic Elevation of Serum Pancreatic Enzymes: How to Deal with It? 158 Giuseppe Vanella, Paolo Giorgio Arcidiacono, and Gabriele Capurso
Section II Chronic Pancreatitis 169
23 Definition and Etiology of Chronic Pancreatitis: What is Relevant for Clinical Practice? 171 David C. Whitcomb
24 Epidemiology of Chronic Pancreatitis: An Infrequent Disease or an Infrequently Diagnosed Disease? 180 Philippe Lévy and Vinciane Rebours
25 Alcoholic Chronic Pancreatitis and the Impact of Alcohol and Smoking Cessation in Chronic Pancreatitis 185 Jeremy S. Wilson, Romano C. Pirola, and Minoti V. Apte
1 Acute Pancreatitis: An Overview 3 Jodie A. Barkin and Jamie S. Barkin
2 How to Deal with the Etiological Diagnosis of Acute Pancreatitis in Clinical Practice? 17 Soumya Jagannath and Pramod Kumar Garg
3 Definition of Complications and Severity of Acute Pancreatitis for Clinical Practice 25 David X. Jin, Peter A. Banks, and Julia McNabb-Baltar
4 Early Prediction of Severity in Acute Pancreatitis: What can be Done in Clinical Practice? 31 Peter J. Lee and Georgios I. Papachristou
5 Role of CT Scan in Acute Pancreatitis: When is it Indicated and What Information can be Obtained? 40 Elham Afghani, Mahya Faghih, and Vikesh K. Singh
6 Role of MRI in Acute Pancreatitis: When is it Indicated and What Information can be Obtained? 47 Fatih Akisik
7 Treatment of Acute Pancreatitis in The Emergency Room: What Should be Done During the First Hours of Disease? 53 Thiruvengadam Muniraj and Santhi Swaroop Vege
8 Acute Pancreatitis: A Practical Guideline for the Monitoring and Treatment of Systemic Complications 59 Enrique de Madaria and Felix Zubia-Olaskoaga
9 Guidelines for the Treatment of Pain in Acute Pancreatitis 66 László Czakó
10 Nutrition in the Acute Phase of Pancreatitis: Why, When, How and How Long? 72 Angela Pham and Chris E. Forsmark
11 Oral Refeeding in Acute Pancreatitis: When and How Should it be Restarted? 78 José Lariño-Noia and Daniel de la Iglesia-García
12 Pharmacological Therapy for Acute Pancreatitis: Any Light at the End of the Tunnel? 83 Rajarshi Mukherjee, Muhammad Awais, Wenhao Cai, Wei Huang, Peter Szatmary, and Robert Sutton
13 Indication and Optimal Timing of ERCP in Acute Pancreatitis 95 Theodor Voiosu, Ivo Boskoski, and Guido Costamagna
14 How to Deal with Infected Pancreatic Necrosis? 100 J. Enrique Domínguez-Muñoz
15 Minimally Invasive Surgical Necrosectomy in Clinical Practice: Indications, Technical Issues, and Optimal Timing 105 Patricia Sánchez-Velázquez, Fernando Burdío, and Ignasi Povesi
16 Endoscopic Necrosectomy in Clinical Practice: Indications, Technical Issues and Optimal Timing 113 Jodie A. Barkin and Andres Gelrud
17 Management of Acute Pancreatic Pseudocyst: When to Observe, When and How to Drain? 120 Muhammad F. Dawwas and Kofi W. Oppong
18 The Disconnected Main Pancreatic Duct Syndrome: How to Proceed in Clinical Practice? 126 Mario Peláez-Luna, Andrea Soriano-Ríos, and Luis Uscanga-Dominguez
19 Vasculature Complications in Pancreatitis: How to Deal with Them? 132 Daniel G. McCall and Timothy B. Gardner
20 Acute Relapsing Pancreatitis: What can be Done to Prevent Relapses? 141 Jorge D. Machicado and Dhiraj Yadav
21 Diagnosis and Therapeutic Approach to Pancreatic Exocrine Insufficiency after Acute Pancreatitis 151 Hester C. Timmerhuis, Christa J. Sperna Weiland, and Hjalmar C. van Santvoort
22 Asymptomatic Chronic Elevation of Serum Pancreatic Enzymes: How to Deal with It? 158 Giuseppe Vanella, Paolo Giorgio Arcidiacono, and Gabriele Capurso
Section II Chronic Pancreatitis 169
23 Definition and Etiology of Chronic Pancreatitis: What is Relevant for Clinical Practice? 171 David C. Whitcomb
24 Epidemiology of Chronic Pancreatitis: An Infrequent Disease or an Infrequently Diagnosed Disease? 180 Philippe Lévy and Vinciane Rebours
25 Alcoholic Chronic Pancreatitis and the Impact of Alcohol and Smoking Cessation in Chronic Pancreatitis 185 Jeremy S. Wilson, Romano C. Pirola, and Minoti V. Apte
26 What is Relevant on Genetics in Chron
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