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This book provides an overview of planning and examining the methodology, analytic issues, primary and secondary endpoints and outcomes in headache trials. Throughout the book, guidance on how to design a high quality study and how to evaluate which study has relevant scientific qualification is discussed in detail. Clinical scales and patient related outcome measures (PROMs) to exclude secondary headaches, to diagnose primary headache disorders, to evaluate patients’ health-related quality of life, to detect psychiatric comorbidities, to assess patients’ headache-related disability and to…mehr
This book provides an overview of planning and examining the methodology, analytic issues, primary and secondary endpoints and outcomes in headache trials. Throughout the book, guidance on how to design a high quality study and how to evaluate which study has relevant scientific qualification is discussed in detail. Clinical scales and patient related outcome measures (PROMs) to exclude secondary headaches, to diagnose primary headache disorders, to evaluate patients’ health-related quality of life, to detect psychiatric comorbidities, to assess patients’ headache-related disability and to monitor patients’ treatment optimization are clearly and concisely outlined in the chapters.
Clinical Scales for Headache Disorders highlights the components for planning an effective headache study including interpretation of primary and secondary endpoints, common clinical scales, PROMs and their clinical reliability and validation. Both clinicians and researchers willfind this book to be a useful tool for their medical and academic practices on headache and migraine.
Pınar Yalınay Dikmen, MD is a neurologist, a neurophysiologist working as a professor at the Department of Neurology, Acıbadem University, School of Medicine, Istanbul, Turkey. She graduated from Istanbul University, Cerrahpaşa Medical Faculty and completed a Master of Science degree in Neurophysiology from Istanbul University, the Institute of Health Sciences. Professor Yalınay Dikmen entitled as Fellow of the European Board of Neurology in 2013. Her primary areas of interest and work are clinical headache studies and electrophysiology.
Aynur Özge, MD is Professor at the Department of Neurology at Mersin University, Faculty of Medicine, Mersin, Turkey. She is a co-editor of the books “Headache in Children and Adolescents: A Case-Based Approach”, “Headache and Comorbidities in Childhood and Adolescence” and “Peripheral Interventional Headache Management”, published by Springer in 2016, 2017, 2019, respectively.
Professor Özge has been an active member of the IHS since 2003 and joined the Pediatric SIG in 2004. She was President of the 12th International Congress of Childhood and Adolescence in 2008 and participated in the European Headache Federation Guideline Committee’s studies for the declaration of Guidelines for the Childhood Headache. Professor Özge is a member of MENA Headache education program and President of Global Migraine and Pain Summit for 2020 and 2021. Her primary fields of interest are epidemiology of headache, comorbidity, headache database systems, childhood and adolescent headaches, dementia clinic and caregiving supporting models.
Inhaltsangabe
What is the best methodology for headache or migraine research?.- Clinical Scales for Headache and Migraine.- Reliability and Validity of Measurement of Clinical Scales .- PROMs in headache and migraine.- Measuring pain intensity in headache trials.- Clinical Scales for diagnosing and screening of headache and migraine.- Clinical Scales for disability, impact and burden in headache and migraine. Clinical Scales for health-related quality of life in headache and migraine: generic and disease-specific.- Clinical Scales for psychiatric comorbidities and cognitive processes in headache and migraine.- Clinical Scales for treatment monitoring and optimization in headache and migraine.- Other Questionnaires We Don’t Want to Miss in Headache Studies.- Clinical Scales for Various Groups.
What is the best methodology for headache or migraine research?.- Clinical Scales for Headache and Migraine.- Reliability and Validity of Measurement of Clinical Scales .- PROMs in headache and migraine.- Measuring pain intensity in headache trials.- Clinical Scales for diagnosing and screening of headache and migraine.- Clinical Scales for disability, impact and burden in headache and migraine. Clinical Scales for health-related quality of life in headache and migraine: generic and disease-specific.- Clinical Scales for psychiatric comorbidities and cognitive processes in headache and migraine.- Clinical Scales for treatment monitoring and optimization in headache and migraine.- Other Questionnaires We Don’t Want to Miss in Headache Studies.- Clinical Scales for Various Groups.
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