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Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will…mehr
Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis.
This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.
Dr. Nagaraju GP is a faculty member in the Department of Hematology and Medical Oncology at Emory University School of Medicine. Dr. Nagaraju obtained his MSc and PhD, both in biotechnology from Sri Venkateswara University in Tirupati, Andhra Pradesh, India. Dr. Nagaraju received his D.Sc. from Berhampur University in Berhampur, Odisha, India. Dr. Nagaraju's research focuses on translational research in gastrointestinal malignancies. He has published over 90 research papers in highly respected international journals and has presented more than 50 abstracts at various national and international conferences. He is author and editor of several books. Dr. Nagaraju is an editorial board member of several internationally recognized academic journals, and is an associate member of the Discovery and Developmental Therapeutics research program at Winship Cancer Institute. He is a member of the Association of Scientists of Indian Origin in America (ASIOA), the Society for Integrative and Comparative Biology (SICB), the Science Advisory Board, The RNA Society and the American Association of Cancer Research (AACR).
Dr. Dhananjay Shukla is an Assistant Professor in the Department of Biotechnology at Guru Ghasidas Vishwavidyalaya (A Central University) in India. Dr. Shukla received his PhD in Biotechnology from Jamia Hamdard University. He is a member of the Indian Immunological Society and Indian Science Congress. He has presented and been invited to lecture at a number of national meetings in India.
Dr. Naveen Kumar Vishvakarma is an Assistant Professor in the Department of Biotechnology at Guru Ghasidas Vishwavidyalaya (A Central University) in India. Dr. Vishvakarma received his PhD in Biotechnology from Banaras Hindu University. He has written a number of book chapters and been invited to lecture at a dozens of national meetings in India.
Inhaltsangabe
1. Application of Single Cell Technology in Colorectal Cancer 2. Dietary habits and global incidence of Colon Cancer 3. Diet and Colon Cancer: A Comprehensive Review 4. Recent therapeutic strategies for the treatment of colon cancer 5. Role of bacteria in development of cancer 6. Role of Bacterial infection (H. Pylori) in colon carcinogenesis and therapeutic approaches 7. Diagnosis of Colorectal Cancer using Molecular Techniques 8. Nanotechnology approaches for colorectal cancer diagnosis and therapy 9. Natural products as immunomodulatory and chemo-sensitizing agents in colon cancer treatment 10. Role of DNA mismatch repair genes in colorectal cancer 11. Targeting of aerobic glycolysis: an emerging therapeutic approach against colon cancer 12. An insight into therapeutic potential of phytochemicals for colorectal cancer: Latest perspective 13. Sea weeds: Potential candidates in human colon cancer therapy 14. Recent update on Nanomedicine based drug targeting on colon cancer 15. Therapeutic targeting of glutamine metabolism in colorectal cancer 16. Preventive effect of indian food on colorectal cancer 17. Extracellular Vesicles in Colorectal Cancer Progress, Metastasis, Diagnosis and Therapy 18. Probiotics in colon cancer: A therapeutic approach Index
1. Application of Single Cell Technology in Colorectal Cancer2. Dietary habits and global incidence of Colon Cancer3. Diet and Colon Cancer: A Comprehensive Review4. Recent therapeutic strategies for the treatment of colon cancer5. Role of bacteria in development of cancer6. Role of Bacterial infection (H. Pylori) in colon carcinogenesis and therapeutic approaches7. Diagnosis of Colorectal Cancer using Molecular Techniques8. Nanotechnology approaches for colorectal cancer diagnosis and therapy9. Natural products as immunomodulatory and chemo-sensitizing agents in colon cancer treatment10. Role of DNA mismatch repair genes in colorectal cancer11. Targeting of aerobic glycolysis: an emerging therapeutic approach against colon cancer12. An insight into therapeutic potential of phytochemicals for colorectal cancer: Latest perspective13. Sea weeds: Potential candidates in human colon cancer therapy14. Recent update on Nanomedicine based drug targeting on colon cancer15. Therapeutic targeting of glutamine metabolism in colorectal cancer16. Preventive effect of indian food on colorectal cancer17. Extracellular Vesicles in Colorectal Cancer Progress, Metastasis, Diagnosis and Therapy18. Probiotics in colon cancer: A therapeutic approachIndex
1. Application of Single Cell Technology in Colorectal Cancer 2. Dietary habits and global incidence of Colon Cancer 3. Diet and Colon Cancer: A Comprehensive Review 4. Recent therapeutic strategies for the treatment of colon cancer 5. Role of bacteria in development of cancer 6. Role of Bacterial infection (H. Pylori) in colon carcinogenesis and therapeutic approaches 7. Diagnosis of Colorectal Cancer using Molecular Techniques 8. Nanotechnology approaches for colorectal cancer diagnosis and therapy 9. Natural products as immunomodulatory and chemo-sensitizing agents in colon cancer treatment 10. Role of DNA mismatch repair genes in colorectal cancer 11. Targeting of aerobic glycolysis: an emerging therapeutic approach against colon cancer 12. An insight into therapeutic potential of phytochemicals for colorectal cancer: Latest perspective 13. Sea weeds: Potential candidates in human colon cancer therapy 14. Recent update on Nanomedicine based drug targeting on colon cancer 15. Therapeutic targeting of glutamine metabolism in colorectal cancer 16. Preventive effect of indian food on colorectal cancer 17. Extracellular Vesicles in Colorectal Cancer Progress, Metastasis, Diagnosis and Therapy 18. Probiotics in colon cancer: A therapeutic approach Index
1. Application of Single Cell Technology in Colorectal Cancer2. Dietary habits and global incidence of Colon Cancer3. Diet and Colon Cancer: A Comprehensive Review4. Recent therapeutic strategies for the treatment of colon cancer5. Role of bacteria in development of cancer6. Role of Bacterial infection (H. Pylori) in colon carcinogenesis and therapeutic approaches7. Diagnosis of Colorectal Cancer using Molecular Techniques8. Nanotechnology approaches for colorectal cancer diagnosis and therapy9. Natural products as immunomodulatory and chemo-sensitizing agents in colon cancer treatment10. Role of DNA mismatch repair genes in colorectal cancer11. Targeting of aerobic glycolysis: an emerging therapeutic approach against colon cancer12. An insight into therapeutic potential of phytochemicals for colorectal cancer: Latest perspective13. Sea weeds: Potential candidates in human colon cancer therapy14. Recent update on Nanomedicine based drug targeting on colon cancer15. Therapeutic targeting of glutamine metabolism in colorectal cancer16. Preventive effect of indian food on colorectal cancer17. Extracellular Vesicles in Colorectal Cancer Progress, Metastasis, Diagnosis and Therapy18. Probiotics in colon cancer: A therapeutic approachIndex
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