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Inhaltsangabe
1 Introduction.- 2 The Spectram of Inflammatory Demyelinating Diseases.- 2.1 Experimental Models.- 2.2 Human Diseases.- 3 Allergic Encephalomyelitis in Humans.- 4 The Pathology of Inflammatory Demyelinating Lesions.- 4.1 Inflammatory Reaction.- 4.2 Vascular Pathology.- 4.3 Blood-Brain Barrier.- 4.4 Demyelination and Myelin Degradation.- 4.5 The Fate of Oligodendroglia.- 4.6 Remyelination.- 4.7 Sclerosis.- 4.8 Axonal and Neuronal Pathology.- 4.9 Meningeal Pathology.- 4.10 Peripheral Nervous System Pathology.- 4.11 Patterns of Plaque Growth.- 4.12 Lesional Topography in the CNS.- 4.13 The Variability of Inflammatory Demyelinating Lesions.- 4.14 EAE as a Model of Human Inflammatory Demyelinating Diseases.- 5 Immunopathogenetic Considerations.- 5.1 Transfer Studies.- 5.2 The Possible Role of Autoantigens in the Pathogenesis of Inflammatory Demyelinating Lesions.- 5.3 Conclusions.- 6 Addendum: Material and Methods - Models of Chronic EAE.- 6.1 Material and Methods.- 6.2 Factors Modifying the Development of Chronic EAE Models.- 7 References.
1 Introduction.- 2 The Spectram of Inflammatory Demyelinating Diseases.- 2.1 Experimental Models.- 2.2 Human Diseases.- 3 Allergic Encephalomyelitis in Humans.- 4 The Pathology of Inflammatory Demyelinating Lesions.- 4.1 Inflammatory Reaction.- 4.2 Vascular Pathology.- 4.3 Blood-Brain Barrier.- 4.4 Demyelination and Myelin Degradation.- 4.5 The Fate of Oligodendroglia.- 4.6 Remyelination.- 4.7 Sclerosis.- 4.8 Axonal and Neuronal Pathology.- 4.9 Meningeal Pathology.- 4.10 Peripheral Nervous System Pathology.- 4.11 Patterns of Plaque Growth.- 4.12 Lesional Topography in the CNS.- 4.13 The Variability of Inflammatory Demyelinating Lesions.- 4.14 EAE as a Model of Human Inflammatory Demyelinating Diseases.- 5 Immunopathogenetic Considerations.- 5.1 Transfer Studies.- 5.2 The Possible Role of Autoantigens in the Pathogenesis of Inflammatory Demyelinating Lesions.- 5.3 Conclusions.- 6 Addendum: Material and Methods - Models of Chronic EAE.- 6.1 Material and Methods.- 6.2 Factors Modifying the Development of Chronic EAE Models.- 7 References.
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