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This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike. *Over 100 chapters conveniently divided into 3 sections *Represents a 'one-stop-shop' of information…mehr
This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike.
*Over 100 chapters conveniently divided into 3 sections *Represents a 'one-stop-shop' of information with suitable indexing of the various pathways and processes *Each chapter is highly illustrated with tables as well as figures
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Inhaltsangabe
Contributors Preface Foreword Volume One Part I: General Aspects of Alcohol Toxicity, Consumption, and Disease Evolutionary and Historical Aspects of Ethanol Ingestion Alcohol Metabolism: General Aspects Intake of Different Alcoholic Beverages and Life-style and Psychosocial Factors Genetic Aspects of Alcohol Metabolism: An Overview Predictors of Alcohol Consumption Binge Drinking: Patterns, Explanations, and Policy Breath and Blood Alcohol Effects of Food and Body Composition on Blood Alcohol Levels Disposal of Ethanol Carbon Atoms Effect of Alcohol on Water and Sodium Homeostasis Energy from Alcohol The Mediterranean Diet and the Contribution and Role of Alcohol The Role of Alcohol in Injury Deaths Death from Alcohol Poisoning Alcohol and the Workplace Alcohol Misuse in Adolescents: Epidemiology, Clinical Characteristics, Diagnosis, and Treatment Alcohol Misuse in Adolescents: Individual Differences, Prevention, Identification, and Intervention What is the Impact of Alcohol on Learning in University Students? The Relationship Between Alcohol Misuse and the Homelessness Alcohol and Sport Activities: Spectator's Perspective Part II: Damage/Disease General Aspects of Pathology An Overview of Pathologies Occurring in Alcohol Abusers Gender Differences in Alcohol Pathology Psychological Effects of Alcohol Misuse The Effect of Alcohol on Quality of Life Alcohol and Road Accidents Trauma and Alcohol Clinical Implications of Alcohol Misuse for Surgery Fetal Alcohol Spectrum Disorder Nutritional Status in Alcoholics Alcohol and Body Composition Beneficial Components of White Wine Polyphenols and Alcohol: Complementary Mechanisms for the Protective Effects of Moderate Wine Consumption Overview of ALDH Polymorphism: Relation to Cardiovascular Effects of Alcohol Overview on the Effects of Amount and Type of Alcohol on Morbidity and Mortality Alcohol-related Mortality in Russia (ii) Organ Damage Epidemiology and Risk Factors Involved in Alcoholic Liver Disease Polymorphism and Alcoholic Liver Disease Liver Injury During Alcohol Use and Withdrawal Alcohol Consumption and Diabetes Mellitus Alcoholic Ketoacidosis Alcohol, Alcoholism and Effects on the Kidney and Kidney Disease Alcohol Intake and the Lower Urinary Tract Alcohol and Prostate Cancer Oral Health and Alcohol Volume 2 Alcohol and the Gastrointestinal Tract Alcohol, ALDH2 Genotypes and Intestinal Cancer Alcohol and Pancreatitis The Skin and Alcohol Alcohol, Blood Pressure and Hypertension Alcohol and Stroke Alcoholic Cardiomyopathy Epidemiologic Aspects of ALDH2 Genotypes and Cardiovascular Parameters Alcoholic Myopathy: Clinical Aspects Alcohol and the Eye: Friend or Foe Marchiafava-Bignami Disease in Alcoholism Peripheral Neuropathy (iii) Cells, Pathways, Interactions, Processes Defects in Methionine Metabolism: Its Role in Ethanol-induced Liver Injury Roles of Kupffer Cells in Alcoholic Liver Disease The Role of the Stellate Cell in Alcohol Mediated Tissue Injury The Role of T Lymphocytes in the Pathogenesis of Alcoholic Liver Disease Oxidative Stress in Alcoholic Liver Disease: Clinical Studies The Relationship between Alcohol-induced Apoptosis and Oxidative Stress in the Liver Alcohol and HIV Interactions in the Natural History and Treatment of HIV/AIDS Alcohol and Hepatitis Virus Interactions in Liver Pathology Moderate Alcohol and Fibrosis in Chronic Viral Hepatitis Ethanol-Taurine Interactions in the Brain: Mechanisms and Pathophysiological Implications The Effect of Ethanol on Ion Channels in the Brain: A New Look A Nitric Oxide Signaling Pathway Protects the Developing Brain against Alcohol-induced Neuronal Death Signaling Pathways in the Heart and Moderate Alcohol Intake Effects of Alcohol on Vascular Function Vascular and Biochemical Effects of Moderate Alcohol Consumption: Mechanisms of Protection Against Cardiovascular Disease Alcohol and Xenobiotics in Placenta Damage Molecular Mechanisms in Fetal Alcohol Syndrome: Shh-signaling The Process of Bacterial Translocation and Implications for Health in Alcoholics Alcohol, Altered Gut Permeability, and Endotoxins Hormonal Responses in Alcoholism Alcohol-induced Changes in the GH-IGF Axis Mechanisms in Prostate Damage by Alcohol Signaling Pathways in Human Breast Cells in Response to Alcohol: Mechanisms for Alcohol-induced Breast Cancer The Ubiquitin-Proteasome System in Alcohol-Induced Pathology Alcohol and Alkylating Agents DNA Damage Resulting from Alcohol Abuse with Special Reference to the Brain Purine Metabolism and the Influence of Alcoholic Beverages The Role of PKC Isozymes in Mediating Responses to Ethanol Ethanol Modulation of cAMP-dependent Protein Kinase Subunits Activity: Mechanisms and Functional Consequences Adhesion Molecules and Alcohol Consumption Glucose-regulated Stress Proteins (GRPs) and Alcohol Heat Shock Proteins and Alcohol Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction Alcohol and Apoptosis Volume 3 Alcohol and Fatty Acid Ethyl Esters Modification of Proteins by Reactive Ethanol Metabolites: Adduct Structure, Functional and Pathological Consequences The Effect of Acetaldehyde on Plasma Autoantibodies in Alcohol-related Tissue Diseases Alcohol-induced Membrane Damage Alcohol Abuse and Eating Disorders The Relationship Between Obesity and Alcoholic Pathology Protein Deficiency and Alcohol: Interactions and Organ Effects Tryptophan Metabolism and Alcoholism Part III: Selective Methods Used in Alcohol Research Selective Methods Used in Alcohol Research: Screening in Primary Care - Methods and Approaches Psychometric Assessment of Alcohol Use Self-reported Intake of Alcohol: Methods and Approaches Use of the DSM-IV: Methods and Approaches The Alcohol-related Problems Survey: Developing and Testing a Screening Measure for Older Adults The Rapid Alcohol Problems Screen: Methods and Application Methods for Determining Blood Alcohol Concentration: Current and Retrospective Urinary Markers of Alcohol Consumption Methods for Measuring Genetic Variations in ADH and SLDH Loci: A Practical Approach Histological Localization of Alcohol Dehydrogenase: Methods, Approaches and Applications Assays for Alcohol and Aldehyde Dehydrogenase: Methods, Approaches and Applications Detecting ADH and ALDH Enzymes in Cells and Tissues using Western Blotting Use of Selectively Bred Alcohol-preferring Rats to Study Alcohol Abuse, Relapse and Craving Animal Models of Chronic Alcohol-Induced Liver Damage Acute Ethanol Dosing Regimens: Methods and Approaches Use of Isolated Cells in the Study of Ethanol-Induced Hepatotoxicity Animal Models of Fetal Alcohol Syndrome: Methods and Approaches Genetically Engineered Animals in Alcohol Research cDNA Arrays in Alcohol-Related Pathology: Methods and Approaches Practical Methods for Determining mRNA Levels in Alcohol-Exposed Tissues and Its Application to Experimental Pathology Diagnosis of Fetal Alcohol Syndrome: Measurement of the Facial Dysmorphology Nuclear Magnetic Resonance: Methods and Application to Alcohol Effects in the Liver Index
Contributors Preface Foreword Volume One Part I: General Aspects of Alcohol Toxicity, Consumption, and Disease Evolutionary and Historical Aspects of Ethanol Ingestion Alcohol Metabolism: General Aspects Intake of Different Alcoholic Beverages and Life-style and Psychosocial Factors Genetic Aspects of Alcohol Metabolism: An Overview Predictors of Alcohol Consumption Binge Drinking: Patterns, Explanations, and Policy Breath and Blood Alcohol Effects of Food and Body Composition on Blood Alcohol Levels Disposal of Ethanol Carbon Atoms Effect of Alcohol on Water and Sodium Homeostasis Energy from Alcohol The Mediterranean Diet and the Contribution and Role of Alcohol The Role of Alcohol in Injury Deaths Death from Alcohol Poisoning Alcohol and the Workplace Alcohol Misuse in Adolescents: Epidemiology, Clinical Characteristics, Diagnosis, and Treatment Alcohol Misuse in Adolescents: Individual Differences, Prevention, Identification, and Intervention What is the Impact of Alcohol on Learning in University Students? The Relationship Between Alcohol Misuse and the Homelessness Alcohol and Sport Activities: Spectator's Perspective Part II: Damage/Disease General Aspects of Pathology An Overview of Pathologies Occurring in Alcohol Abusers Gender Differences in Alcohol Pathology Psychological Effects of Alcohol Misuse The Effect of Alcohol on Quality of Life Alcohol and Road Accidents Trauma and Alcohol Clinical Implications of Alcohol Misuse for Surgery Fetal Alcohol Spectrum Disorder Nutritional Status in Alcoholics Alcohol and Body Composition Beneficial Components of White Wine Polyphenols and Alcohol: Complementary Mechanisms for the Protective Effects of Moderate Wine Consumption Overview of ALDH Polymorphism: Relation to Cardiovascular Effects of Alcohol Overview on the Effects of Amount and Type of Alcohol on Morbidity and Mortality Alcohol-related Mortality in Russia (ii) Organ Damage Epidemiology and Risk Factors Involved in Alcoholic Liver Disease Polymorphism and Alcoholic Liver Disease Liver Injury During Alcohol Use and Withdrawal Alcohol Consumption and Diabetes Mellitus Alcoholic Ketoacidosis Alcohol, Alcoholism and Effects on the Kidney and Kidney Disease Alcohol Intake and the Lower Urinary Tract Alcohol and Prostate Cancer Oral Health and Alcohol Volume 2 Alcohol and the Gastrointestinal Tract Alcohol, ALDH2 Genotypes and Intestinal Cancer Alcohol and Pancreatitis The Skin and Alcohol Alcohol, Blood Pressure and Hypertension Alcohol and Stroke Alcoholic Cardiomyopathy Epidemiologic Aspects of ALDH2 Genotypes and Cardiovascular Parameters Alcoholic Myopathy: Clinical Aspects Alcohol and the Eye: Friend or Foe Marchiafava-Bignami Disease in Alcoholism Peripheral Neuropathy (iii) Cells, Pathways, Interactions, Processes Defects in Methionine Metabolism: Its Role in Ethanol-induced Liver Injury Roles of Kupffer Cells in Alcoholic Liver Disease The Role of the Stellate Cell in Alcohol Mediated Tissue Injury The Role of T Lymphocytes in the Pathogenesis of Alcoholic Liver Disease Oxidative Stress in Alcoholic Liver Disease: Clinical Studies The Relationship between Alcohol-induced Apoptosis and Oxidative Stress in the Liver Alcohol and HIV Interactions in the Natural History and Treatment of HIV/AIDS Alcohol and Hepatitis Virus Interactions in Liver Pathology Moderate Alcohol and Fibrosis in Chronic Viral Hepatitis Ethanol-Taurine Interactions in the Brain: Mechanisms and Pathophysiological Implications The Effect of Ethanol on Ion Channels in the Brain: A New Look A Nitric Oxide Signaling Pathway Protects the Developing Brain against Alcohol-induced Neuronal Death Signaling Pathways in the Heart and Moderate Alcohol Intake Effects of Alcohol on Vascular Function Vascular and Biochemical Effects of Moderate Alcohol Consumption: Mechanisms of Protection Against Cardiovascular Disease Alcohol and Xenobiotics in Placenta Damage Molecular Mechanisms in Fetal Alcohol Syndrome: Shh-signaling The Process of Bacterial Translocation and Implications for Health in Alcoholics Alcohol, Altered Gut Permeability, and Endotoxins Hormonal Responses in Alcoholism Alcohol-induced Changes in the GH-IGF Axis Mechanisms in Prostate Damage by Alcohol Signaling Pathways in Human Breast Cells in Response to Alcohol: Mechanisms for Alcohol-induced Breast Cancer The Ubiquitin-Proteasome System in Alcohol-Induced Pathology Alcohol and Alkylating Agents DNA Damage Resulting from Alcohol Abuse with Special Reference to the Brain Purine Metabolism and the Influence of Alcoholic Beverages The Role of PKC Isozymes in Mediating Responses to Ethanol Ethanol Modulation of cAMP-dependent Protein Kinase Subunits Activity: Mechanisms and Functional Consequences Adhesion Molecules and Alcohol Consumption Glucose-regulated Stress Proteins (GRPs) and Alcohol Heat Shock Proteins and Alcohol Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction Alcohol and Apoptosis Volume 3 Alcohol and Fatty Acid Ethyl Esters Modification of Proteins by Reactive Ethanol Metabolites: Adduct Structure, Functional and Pathological Consequences The Effect of Acetaldehyde on Plasma Autoantibodies in Alcohol-related Tissue Diseases Alcohol-induced Membrane Damage Alcohol Abuse and Eating Disorders The Relationship Between Obesity and Alcoholic Pathology Protein Deficiency and Alcohol: Interactions and Organ Effects Tryptophan Metabolism and Alcoholism Part III: Selective Methods Used in Alcohol Research Selective Methods Used in Alcohol Research: Screening in Primary Care - Methods and Approaches Psychometric Assessment of Alcohol Use Self-reported Intake of Alcohol: Methods and Approaches Use of the DSM-IV: Methods and Approaches The Alcohol-related Problems Survey: Developing and Testing a Screening Measure for Older Adults The Rapid Alcohol Problems Screen: Methods and Application Methods for Determining Blood Alcohol Concentration: Current and Retrospective Urinary Markers of Alcohol Consumption Methods for Measuring Genetic Variations in ADH and SLDH Loci: A Practical Approach Histological Localization of Alcohol Dehydrogenase: Methods, Approaches and Applications Assays for Alcohol and Aldehyde Dehydrogenase: Methods, Approaches and Applications Detecting ADH and ALDH Enzymes in Cells and Tissues using Western Blotting Use of Selectively Bred Alcohol-preferring Rats to Study Alcohol Abuse, Relapse and Craving Animal Models of Chronic Alcohol-Induced Liver Damage Acute Ethanol Dosing Regimens: Methods and Approaches Use of Isolated Cells in the Study of Ethanol-Induced Hepatotoxicity Animal Models of Fetal Alcohol Syndrome: Methods and Approaches Genetically Engineered Animals in Alcohol Research cDNA Arrays in Alcohol-Related Pathology: Methods and Approaches Practical Methods for Determining mRNA Levels in Alcohol-Exposed Tissues and Its Application to Experimental Pathology Diagnosis of Fetal Alcohol Syndrome: Measurement of the Facial Dysmorphology Nuclear Magnetic Resonance: Methods and Application to Alcohol Effects in the Liver Index
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