Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases (eBook, PDF)

Redaktion: Devillers, James

• Format: PDF

Produktbeschreibung

There is a compelling need for new drugs and efficient treatments against mosquito-borne diseases. Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases explains how the search for new substances effective against mosquitoes and their diseases has benefited from the use of in silico techniques.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 482
• Erscheinungstermin: 15. Dezember 2017
• Englisch
• ISBN-13: 9781498741811
• Artikelnr.: 50518977

Autorenporträt

PhD in ecotoxicology (1987, University Lyon I, France). Head of CTIS. Publications: 245 peer-reviewed papers and book chapters. 15 authored/edited books. Founding editor (1993) and editor-in-chief (1993 to present) of the journal SAR and QSAR in Environmental Research (Gordon & Breach Science Publishers and now Taylor & Francis). Co-Editor of the journal Toxicology Methods (Taylor & Francis, 1997 to 2002). Member of the editorial board of: Journal of Biological Systems (World Scientific, 1995 to 1997). Toxicology Mechanisms and Methods (Taylor & Francis, 2002 to 2009). Current Bioactive Compounds (Bentham Science Publishers, 2007 to 2014). Ecological Modelling (Elsevier, 1996 to present). Xenobiotica (Informa Healthcare, 1995 to present). Toxics (MDPI AG, 2013 to present). Organization or co-organization of 14 international meetings.

Inhaltsangabe

Contents. Series Introduction. Acknowledgments. Contributors. Chapter 1
Repurposing Insecticides and Drugs for the Control of Mosquitoes and their
Diseases. Chapter 2 Insect Olfactory System as the Target for
Computer-Aided Design of Mosquito Repellents. Chapter 3
OBP-Structure-Aided Repellent Discovery: An Emerging Tool towards the
Prevention of Mosquito-Borne Diseases. Chapter 4 Molecular Topology as a
Powerful Tool for Searching new Repellents and Novel Drugs against Diseases
Transmitted by Mosquitoes. Chapter 5 Pharmacophore modeling applied to
mosquito borne diseases. Chapter 6 Comparative MIA-QSAR Proteochemometric
Analysis of NS3 Protease Substrates in Dengue Virus. Chapter 7
Mosquito-Active Cry d -Endotoxins from Bacillus thuringiensis subsp.
israelensis: Structural Insights into the Toxin-Induced Pore Architecture.
Chapter 8 Structural Scaffolding for New Mosquito Larvicides. 9 SAR and
QSAR Modeling of Structurally Diverse Juvenoids Active on Mosquito Larvae.
Chapter 10 SAR predictions of benzoylphenylurea chitin synthesis inhibitors
active on larvae of Aedes aegypti. Chapter 11 Predicting the toxicity of
piperidines against female adults of Aedes aegypti. Chapter 12 Molecular
modeling studies of the inhibition by natural compounds of a mosquito
detoxification system, implication in mosquito vector control. Chapter 13
Critical review of models for exposure assessment of residents and
bystanders to adulticides used in mosquito control. Chapter 14
Occupational exposure scenarios and modeling in vector control. Chapter 15
Use of insecticides indoor for the control of mosquitoes: Exposure
scenarios and modeling. Index