Cortico-Subcortical Dynamics in Parkinson's Disease (eBook, PDF)

Redaktion: Tseng, Kuei-Yuan

• Format: PDF

Produktbeschreibung

Cortico-subcortical dynamics in Parkinson's disease aims to integrate key pathophysiological aspects underlying Parkinson's disease. The volume offers a broad spectrum of opinions on how chronic dopamine depletion affects cortico-subcortical dynamics, especially how disruptions of the non-dopaminergic systems resulting from chronic dopaminergic degeneration could lead to the functional alterations observed in parkinsonism.

About the Editor:

Dr. Kuei Y. Tseng is Assistant Professor in the Department of Cellular and Molecular Pharmacology at Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, IL, USA.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 316
• Erscheinungstermin: 20. April 2009
• Englisch
• ISBN-13: 9781603272520
• Artikelnr.: 37349344

Inhaltsangabe

Cortico-Subcortical Circuits and Parkinson's Disease.- Leading Toward a Unified Cortico-basal Ganglia Functional Model.- Modeling Parkinson's Disease: 50 Years Later.- Physiological Studies of the Cortico-subcortical Dynamics and Parkinson's Disease.- Phasic Dopaminergic Signaling: Implications for Parkinson's Disease.- Striatal Dendritic Adaptations in Parkinson's Disease Models.- Diversity of Up-State Voltage Transitions During Different Network States.- The Corticostriatal Pathway in Parkinson's Disease.- Cholinergic Interneuron and Parkinsonism.- Basal Ganglia Network Synchronization in Animal Models of Parkinson's Disease.- Converging into a Unified Model of Parkinson's Disease Pathophysiology.- The Corticostriatal Transmission in Parkinsonian Animals: In Vivo Studies.- Striatal Nitric Oxide-cGMP Signaling in an Animal Model of Parkinson's Disease.- Dopamine-Endocannabinoid Interactions in Parkinson's Disease.- Glutamate Plasticity in an Animal Model of Parkinson's Disease.- Computational Analyses of the Cortico-Subcortical Dynamics and Parkinson's Disease.- Neuromodulation and Neurodynamics of Striatal Inhibitory Networks: Implications for Parkinson's Disease.- Dopaminergic Modulation of Corticostriatal Interactions and Implications for Parkinson's Disease.- Neurobiology and Pathophysiology of Parkinson's Disease.- Pathogenesis of Oxidative Stress and the Destructive Cycle in the Substantia Nigra in Parkinson's Disease.- Regulation of G-Protein-Coupled Receptor (GPCR) Trafficking in the Striatum in Parkinson's Disease.- Atypical Parkinsonism in the French West Indies: The Plant Toxin Annonacin as a Potential Etiological Factor.- Cognitive Deficits in Parkinson's Disease.- Pharmacological and Non-Pharmacological Treatments inParkinson's Disease.- Dopamine Replacement Therapy in Parkinson's Disease: Past, Present and Future.- Molecular, Cellular and Electrophysiological Changes Triggered by High-Frequency Stimulation of the Subthalamic Nucleus in Animal Models of Parkinson's Disease.- Surgical Strategies for Parkinson's Disease Based on Animal Model Data: GPi and STN Inactivation on Various Aspects of Behavior (Motor, Cognitive and Motivational Processes).- Antidromic Cortical Activity as the Source of Therapeutic Actions of Deep Brain Stimulation.- Cell-Based Replacement Therapies for Parkinson's Disease.

Rezensionen

From the reviews:

"This book nicely combines up-to-date basic science information with clinical data on one of the most prevalent movement disorders worldwide - Parkinson's disease (PD). ... Written for specialists in Parkinson's disease, the book is appropriate for movement disorder neurologists, neurosurgeons involved in the surgical management of Parkinson's, and basic scientists interested in the anatomy, physiology, and neurochemistry of Parkinson's. ... It is most useful as a reference for basic scientists as well as clinical researchers." (Virgilio Gerald H. Evidente, Doody's Review Service, September, 2009)