Crohn's Disease and Ulcerative Colitis (eBook, PDF)
From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach
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Crohn's Disease and Ulcerative Colitis (eBook, PDF)
From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach
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This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The…mehr
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Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.
- Produktdetails
- Verlag: Springer International Publishing
- Erscheinungstermin: 1. März 2017
- Englisch
- ISBN-13: 9783319337036
- Artikelnr.: 53032974
- Verlag: Springer International Publishing
- Erscheinungstermin: 1. März 2017
- Englisch
- ISBN-13: 9783319337036
- Artikelnr.: 53032974
Inflammatory Bowel Disease Center
Department of Gastroenterology and Hepatology
Charité Medical Center--Virchow Hospital
Medical School of the Humboldt University of Berlin
Berlin, Germany
Chapter 1 Environmental Factors in the Epidemiology of Inflammatory Bowel Disease Morten H. Vatn
Part 2 Immunobiology
Chapter 2 The Intestinal Immune System in Health Per Brandtzaeg
Chapter 3 Understanding the Epithelial Barrier in Inflammatory Bowel Disease Matthew A. Odenwald, Jerrold R. Turner
Chapter 4 Intestinal Microbiology and Ecology in Crohn's Disease and Ulcerative Colitis Dirk Haller, Ludovica F. Butto
Chapter 5 The Immune System in Inflammatory Bowel Disease: Antimicrobial Peptides Charles L. Bevins
Chapter 6 Vascular Responses to Intestinal Inflammation D. Neil Granger, Norman R. Harris
Chapter 7 Immunobiology of Human Dendritic Cells in Inflammatory Bowel Disease Daniel C. Baumgart
Chapter 8 Immunobiology of T-Cells in Inflammatory Bowel Disease S. Snapper, D. Nguyen, A Biswas
Chapter 9 Immunobiology of B cells in Inflammatory Bowel Disease Atsushi Mizoguchi, Atul K. Bhan
Chapter 10 Immune Cells: Monocytes and Macrophages Gerhard Rogler
Chapter 11 Immune Functions of Epithelial Cells in Inflammatory Bowel Disease Eric L. Campbell, Sean P. Colgan
Chapter 12 Autophagy and Endoplasmic Reticulum Stress Arthur Kaser
Chapter 13 Matrix Metalloproteinases Paolo Biancheri, Thomas T. MacDonald
Chapter 14 Paradigm of T-cell Differentiation in Inflammatory Bowel Disease Takashi Nagaishi, Mamoru Watanabe
Chapter 15 Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal Inflammation Cynthia Reinoso Webb, Matthew B. Grisham
Chapter 16 Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel Disease Jorge O. Múnera, James M. Wells
Part 3 Diagnostic Approach
Chapter 17 Enhanced Endoscopy Ralf Kiesslich
Chapter 18 Magnetic Resonance Enterography Patrik Rogalla, Luis Guimaraes
Chapter 19 Computed Tomography Enterography and Inflammatory Bowel Disease J. G. Fletcher
Chapter 20 Ultrasound in Inflammatory Bowel Disease A. Potthoff, C. Agné, M. Gebel
Chapter 21 Laboratory Evaluation, Including Novel Diagnostic Markers M. Flamant, X. Roblin
Chapter 22 Pathology of Inflammatory Bowel Disease Nora E. Joseph, Christopher R. Weber
Chapter 23 Objective Assessment of Clinical Disease Activity Edouard Louis, Catherine Van Kemseke, Catherine Reenaers
Chapter 24 Objective Assessment of Endoscopic Disease Activity and Mucosal Healing Britt Christensen, David T. Rubin
Chapter 25 Evaluation of Quality of Life in Crohn's disease and Ulcerative Colitis: What Is Health-Related Quality of Life? Katrine Carlsen, Pia Munkholm, Johan Burisch
Chapter 26 Evaluation of Health Economics in Inflammatory Bowel Disease Reena Khanna, Brian G. Feagan
Part 4 Therapy Crohn’s Disease
Chapter 27 The Natural History of Inflammatory Bowel Disease Charles N. Bernstein
Chapter 28 Conventional Medica Management of Crohn's Disease: Sulfasalazine Miquel A. Gassull, Eduard Cabré
Chapter 29 Steroid Therapy for Crohn's Disease A. Hillary Steinhart
Chapter 30 Thiopurines in Crohns' disease Adi Lahat, Rami Eliakim
Chapter 31 Conventional Medical Management of Crohn's Disease: Methotrexate Grace Harkin, Laurence Egan
Chapter 32 Adalimumab for the Treatment of Crohn’s Disease Remo Panaccione
Chapter 33 Biologic Therapy of Crohn's Disease: Certolizumab Alessandro Armuzzi, Daniela Pugliese
Chapter 34 Biologic Therapy of Crohn's Disease: Infliximab Jan-Michael A. Klapproth, Gary R. Lichtenstein
Chapter 35 Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease Treatment Peter J. Mannon
Chapter 36 Biologic Therapy of Crohn's Disease: Natalizumab, Vedolizumab and anti-MadCAM Pieter Hindryckx, Geert D’Haens
Chapter 37 Optimal Management of Fistulizing Crohn's Disease Bruce Sands, Farhad Peerani
Part 5 Therapy Ulcerative Colitis
Chapter 38 Sulfasalazine and 5-Aminosalicylates for Ulcerative Colitis Reena Khanna, John K. Marshall
Chapter 39 Conventional Therapy of Ulcerative Colitis: Corticosteroids Kirstin Taylor, Peter R. Gibson
Chapter 40 Medical Management of Ulcerative Colitis: Conventional Therapy--Azathioprine Barrett G. Levesque, Edward V. Loftus
Chapter 41 Calcineurin Inhibitors in Ulcerative Colitis Andreas Fischer, Daniel C. Baumgart
Chapter 42 Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: Infliximab Mindy Lam, Brian Bressler
Chapter 43 Biologic Therapy of Ulcerative Colitis: Adalimumab Walter Reinisch
Chapter 44 Biologic Therapy of Ulcerative Colitis: Golimumab Mark A. Samaan, Peter M. Irving
Chapter 45 Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAM Severine Vermeire
Chapter 46 Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel Disease Paolo Gionchetti, Carlo Calabrese, Andrea Calafiore, Fernando Rizzello
Chapter 47 Biosimiliars in the Treatment of Inflammatory Bowel Disease Vivian W. Huang, Richard N. Fedorak
Chapter 48 Step-up vs. Top-down Approach in Crohn’s Disease Christine Y. Yu, Daniel W. Hommes
Chapter 49 Leucocytapheresis Therapy of Inflammatory Bowel Disease Takanori Kanai
Chapter 50 Surgical Management of Crohn's Disease and Ulcerative Colitis Robert R. Cima, John H. Pemberton
Part 6 Extraintestinal Manifestations
Chapter 51 Extraintestinal Manifestations: Autoimmune Hepatitis Michael Manns, Nora Schweitzer
Chapter 52 Primary Sclerosing Cholangitis Roger W. Chapman, Kate D. Williamson
Chapter 53 Autoimmune Pancreatitis and Other Organ Involvement Go Kuwata, Terumi Kamisawa
Chapter 54 Cutaneous and Oral Manifestations of Inflammatory Bowel Disease Caroline P. Allen, Susan M. Burge
Chapter 55 Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel Disease Alistair Tindell, Hanna Johnsson, Iain B. McInnes
Part 7 Nutrition
Chapter 56 Nutrition in Inflammatory Bowel Disease Alan L. Buchman
Part 8 Pregnancy, Family Planning and Pediatric Aspects
Chapter 57 Pregnancy and Fertility in Inflammatory Bowel Disease Rebecca Matro, Uma Mahadevan
Chapter 58 Pediatric Aspects of Inflammatory Bowel Disease Brendan Boyle, Jeffrey S. Hyams
Part 9 Surveillance and Prevention
Chapter 59 Management and Prevention of Infectious Diseases in Irritable Bowel Disease Patients Kristine Macartney, Nigel Crawford
Chapter 60 Incidence of Cancer and Screening in Inflammatory Bowel Disease Jimmy K. Limdi, Francis A. Farraye
Chapter 61 Inflammatory Bowel Diseases: How to Identify High Risk Patients Jacques Cosnes, Harry Sokol
Part 10 Patient Perspective and Resources
Chapter 62 Patient Perspective on Inflammatory Bowel Disease Ayesha Williams, Marjorie Merrick
Chapter 63 Patient Resources in Inflammatory Bowel Disease Sanna Lönnfors, Marco Greco
Chapter 1 Environmental Factors in the Epidemiology of Inflammatory Bowel DiseaseMorten H. Vatn
Part 2 Immunobiology
Chapter 2 The Intestinal Immune System in HealthPer Brandtzaeg
Chapter 3 Understanding the Epithelial Barrier in Inflammatory Bowel DiseaseMatthew A. Odenwald, Jerrold R. Turner
Chapter 4 Intestinal Microbiology and Ecology in Crohn's Disease and Ulcerative ColitisDirk Haller, Ludovica F. Butto
Chapter 5 The Immune System in Inflammatory Bowel Disease: Antimicrobial PeptidesCharles L. Bevins
Chapter 6 Vascular Responses to Intestinal InflammationD. Neil Granger, Norman R. Harris
Chapter 7 Immunobiology of Human Dendritic Cells in Inflammatory Bowel DiseaseDaniel C. Baumgart
Chapter 8 Immunobiology of T-Cells in Inflammatory Bowel DiseaseS. Snapper, D. Nguyen, A Biswas
Chapter 9 Immunobiology of B cells in Inflammatory Bowel DiseaseAtsushi Mizoguchi, Atul K. Bhan
Chapter 10 Immune Cells: Monocytes and MacrophagesGerhard Rogler
Chapter 11 Immune Functions of Epithelial Cells in Inflammatory Bowel DiseaseEric L. Campbell, Sean P. Colgan
Chapter 12 Autophagy and Endoplasmic Reticulum StressArthur Kaser
Chapter 13 Matrix MetalloproteinasesPaolo Biancheri, Thomas T. MacDonald
Chapter 14 Paradigm of T-cell Differentiation in Inflammatory Bowel DiseaseTakashi Nagaishi, Mamoru Watanabe
Chapter 15 Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal InflammationCynthia Reinoso Webb, Matthew B. Grisham
Chapter 16 Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel DiseaseJorge O. Múnera, James M. Wells
Part 3 Diagnostic Approach
Chapter 17 Enhanced EndoscopyRalf Kiesslich
Chapter 18 Magnetic Resonance EnterographyPatrik Rogalla, Luis Guimaraes
Chapter 19 Computed Tomography Enterography and Inflammatory Bowel DiseaseJ. G. Fletcher
Chapter 20 Ultrasound in Inflammatory Bowel DiseaseA. Potthoff, C. Agné, M. Gebel
Chapter 21 Laboratory Evaluation, Including Novel Diagnostic MarkersM. Flamant, X. Roblin
Chapter 22 Pathology of Inflammatory Bowel DiseaseNora E. Joseph, Christopher R. Weber
Chapter 23 Objective Assessment of Clinical Disease ActivityEdouard Louis, Catherine Van Kemseke, Catherine Reenaers
Chapter 24 Objective Assessment of Endoscopic Disease Activity and Mucosal HealingBritt Christensen, David T. Rubin
Chapter 25 Evaluation of Quality of Life in Crohn's disease and Ulcerative Colitis: What Is Health-Related Quality of Life?Katrine Carlsen, Pia Munkholm, Johan Burisch
Chapter 26 Evaluation of Health Economics in Inflammatory Bowel DiseaseReena Khanna, Brian G. Feagan
Part 4 Therapy Crohn's Disease
Chapter 27 The Natural History of Inflammatory Bowel DiseaseCharles N. Bernstein
Chapter 28 Conventional Medica Management of Crohn's Disease: SulfasalazineMiquel A. Gassull, Eduard Cabré
Chapter 29 Steroid Therapy for Crohn's DiseaseA. Hillary Steinhart
Chapter 30 Thiopurines in Crohns' disease Adi Lahat, Rami Eliakim
Chapter 31 Conventional Medical Management of Crohn's Disease: MethotrexateGrace Harkin, Laurence Egan
Chapter 32 Adalimumab for the Treatment of Crohn's Disease Remo Panaccione
Chapter 33 Biologic Therapy of Crohn's Disease: CertolizumabAlessandro Armuzzi, Daniela Pugliese
Chapter 34 Biologic Therapy of Crohn's Disease: InfliximabJan-Michael A. Klapproth, Gary R. Lichtenstein
Chapter 35 Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease TreatmentPeter J. Mannon
Chapter 36 Biologic Therapy of Crohn's Disease: Natalizumab, Vedolizumab and anti-MadCAMPieter Hindryckx, Geert D'Haens
Chapter 37 Optimal Management of Fistulizing Crohn's DiseaseBruce Sands, Farhad Peerani
Part 5 Therapy Ulcerative Colitis
Chapter 38 Sulfasalazine and 5-Aminosalicylates for Ulcerative ColitisReena Khanna, John K. Marshall
Chapter 39 Conventional Therapy of Ulcerative Colitis: CorticosteroidsKirstin Taylor, Peter R. Gibson
Chapter 40 Medical Management of Ulcerative Colitis: Conventional Therapy--AzathioprineBarrett G. Levesque, Edward V. Loftus
Chapter 41 Calcineurin Inhibitors in Ulcerative ColitisAndreas Fischer, Daniel C. Baumgart
Chapter 42 Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: InfliximabMindy Lam, Brian Bressler
Chapter 43 Biologic Therapy of Ulcerative Colitis: AdalimumabWalter Reinisch
Chapter 44 Biologic Therapy of Ulcerative Colitis: GolimumabMark A. Samaan, Peter M. Irving
Chapter 45 Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAMSeverine Vermeire
Chapter 46 Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel DiseasePaolo Gionchetti, Carlo Calabrese, Andrea Calafiore, Fernando Rizzello
Chapter 47 Biosimiliars in the Treatment of Inflammatory Bowel DiseaseVivian W. Huang, Richard N. Fedorak
Chapter 48 Step-up vs. Top-down Approach in Crohn's DiseaseChristine Y. Yu, Daniel W. Hommes
Chapter 49 Leucocytapheresis Therapy of Inflammatory Bowel DiseaseTakanori Kanai
Chapter 50 Surgical Management of Crohn's Disease and Ulcerative ColitisRobert R. Cima, John H. Pemberton
Part 6 Extraintestinal Manifestations
Chapter 51 Extraintestinal Manifestations: Autoimmune HepatitisMichael Manns, Nora Schweitzer
Chapter 52 Primary Sclerosing CholangitisRoger W. Chapman, Kate D. Williamson
Chapter 53 Autoimmune Pancreatitis and Other Organ InvolvementGo Kuwata, Terumi Kamisawa
Chapter 54 Cutaneous and Oral Manifestations of Inflammatory Bowel DiseaseCaroline P. Allen, Susan M. Burge
Chapter 55 Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel DiseaseAlistair Tindell, Hanna Johnsson, Iain B. McInnes
Part 7 Nutrition
Chapter 56 Nutrition in Inflammatory Bowel DiseaseAlan L. Buchman
Part 8 Pregnancy, Family Planning and Pediatric Aspects
Chapter 57 Pregnancy and Fertility in Inflammatory Bowel DiseaseRebecca Matro, Uma Mahadevan
Chapter 58 Pediatric Aspects of Inflammatory Bowel DiseaseBrendan Boyle, Jeffrey S. Hyams
Part 9 Surveillance and Prevention
Chapter 59 Management and Prevention of Infectious Diseases in Irritable Bowel Disease PatientsKristine Macartney, Nigel Crawford
Chapter 60 Incidence of Cancer and Screening in Inflammatory Bowel DiseaseJimmy K. Limdi, Francis A. Farraye
Chapter 61 Inflammatory Bowel Diseases: How to Identify High Risk PatientsJacques Cosnes, Harry Sokol
Part 10 Patient Perspective and Resources
Chapter 62 Patient Perspective on Inflammatory Bowel DiseaseAyesha Williams, Marjorie Merrick
Chapter 63 Patient Resources in Inflammatory Bowel DiseaseSanna Lönnfors, Marco Greco
Chapter 1 Environmental Factors in the Epidemiology of Inflammatory Bowel Disease Morten H. Vatn
Part 2 Immunobiology
Chapter 2 The Intestinal Immune System in Health Per Brandtzaeg
Chapter 3 Understanding the Epithelial Barrier in Inflammatory Bowel Disease Matthew A. Odenwald, Jerrold R. Turner
Chapter 4 Intestinal Microbiology and Ecology in Crohn's Disease and Ulcerative Colitis Dirk Haller, Ludovica F. Butto
Chapter 5 The Immune System in Inflammatory Bowel Disease: Antimicrobial Peptides Charles L. Bevins
Chapter 6 Vascular Responses to Intestinal Inflammation D. Neil Granger, Norman R. Harris
Chapter 7 Immunobiology of Human Dendritic Cells in Inflammatory Bowel Disease Daniel C. Baumgart
Chapter 8 Immunobiology of T-Cells in Inflammatory Bowel Disease S. Snapper, D. Nguyen, A Biswas
Chapter 9 Immunobiology of B cells in Inflammatory Bowel Disease Atsushi Mizoguchi, Atul K. Bhan
Chapter 10 Immune Cells: Monocytes and Macrophages Gerhard Rogler
Chapter 11 Immune Functions of Epithelial Cells in Inflammatory Bowel Disease Eric L. Campbell, Sean P. Colgan
Chapter 12 Autophagy and Endoplasmic Reticulum Stress Arthur Kaser
Chapter 13 Matrix Metalloproteinases Paolo Biancheri, Thomas T. MacDonald
Chapter 14 Paradigm of T-cell Differentiation in Inflammatory Bowel Disease Takashi Nagaishi, Mamoru Watanabe
Chapter 15 Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal Inflammation Cynthia Reinoso Webb, Matthew B. Grisham
Chapter 16 Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel Disease Jorge O. Múnera, James M. Wells
Part 3 Diagnostic Approach
Chapter 17 Enhanced Endoscopy Ralf Kiesslich
Chapter 18 Magnetic Resonance Enterography Patrik Rogalla, Luis Guimaraes
Chapter 19 Computed Tomography Enterography and Inflammatory Bowel Disease J. G. Fletcher
Chapter 20 Ultrasound in Inflammatory Bowel Disease A. Potthoff, C. Agné, M. Gebel
Chapter 21 Laboratory Evaluation, Including Novel Diagnostic Markers M. Flamant, X. Roblin
Chapter 22 Pathology of Inflammatory Bowel Disease Nora E. Joseph, Christopher R. Weber
Chapter 23 Objective Assessment of Clinical Disease Activity Edouard Louis, Catherine Van Kemseke, Catherine Reenaers
Chapter 24 Objective Assessment of Endoscopic Disease Activity and Mucosal Healing Britt Christensen, David T. Rubin
Chapter 25 Evaluation of Quality of Life in Crohn's disease and Ulcerative Colitis: What Is Health-Related Quality of Life? Katrine Carlsen, Pia Munkholm, Johan Burisch
Chapter 26 Evaluation of Health Economics in Inflammatory Bowel Disease Reena Khanna, Brian G. Feagan
Part 4 Therapy Crohn’s Disease
Chapter 27 The Natural History of Inflammatory Bowel Disease Charles N. Bernstein
Chapter 28 Conventional Medica Management of Crohn's Disease: Sulfasalazine Miquel A. Gassull, Eduard Cabré
Chapter 29 Steroid Therapy for Crohn's Disease A. Hillary Steinhart
Chapter 30 Thiopurines in Crohns' disease Adi Lahat, Rami Eliakim
Chapter 31 Conventional Medical Management of Crohn's Disease: Methotrexate Grace Harkin, Laurence Egan
Chapter 32 Adalimumab for the Treatment of Crohn’s Disease Remo Panaccione
Chapter 33 Biologic Therapy of Crohn's Disease: Certolizumab Alessandro Armuzzi, Daniela Pugliese
Chapter 34 Biologic Therapy of Crohn's Disease: Infliximab Jan-Michael A. Klapproth, Gary R. Lichtenstein
Chapter 35 Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease Treatment Peter J. Mannon
Chapter 36 Biologic Therapy of Crohn's Disease: Natalizumab, Vedolizumab and anti-MadCAM Pieter Hindryckx, Geert D’Haens
Chapter 37 Optimal Management of Fistulizing Crohn's Disease Bruce Sands, Farhad Peerani
Part 5 Therapy Ulcerative Colitis
Chapter 38 Sulfasalazine and 5-Aminosalicylates for Ulcerative Colitis Reena Khanna, John K. Marshall
Chapter 39 Conventional Therapy of Ulcerative Colitis: Corticosteroids Kirstin Taylor, Peter R. Gibson
Chapter 40 Medical Management of Ulcerative Colitis: Conventional Therapy--Azathioprine Barrett G. Levesque, Edward V. Loftus
Chapter 41 Calcineurin Inhibitors in Ulcerative Colitis Andreas Fischer, Daniel C. Baumgart
Chapter 42 Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: Infliximab Mindy Lam, Brian Bressler
Chapter 43 Biologic Therapy of Ulcerative Colitis: Adalimumab Walter Reinisch
Chapter 44 Biologic Therapy of Ulcerative Colitis: Golimumab Mark A. Samaan, Peter M. Irving
Chapter 45 Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAM Severine Vermeire
Chapter 46 Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel Disease Paolo Gionchetti, Carlo Calabrese, Andrea Calafiore, Fernando Rizzello
Chapter 47 Biosimiliars in the Treatment of Inflammatory Bowel Disease Vivian W. Huang, Richard N. Fedorak
Chapter 48 Step-up vs. Top-down Approach in Crohn’s Disease Christine Y. Yu, Daniel W. Hommes
Chapter 49 Leucocytapheresis Therapy of Inflammatory Bowel Disease Takanori Kanai
Chapter 50 Surgical Management of Crohn's Disease and Ulcerative Colitis Robert R. Cima, John H. Pemberton
Part 6 Extraintestinal Manifestations
Chapter 51 Extraintestinal Manifestations: Autoimmune Hepatitis Michael Manns, Nora Schweitzer
Chapter 52 Primary Sclerosing Cholangitis Roger W. Chapman, Kate D. Williamson
Chapter 53 Autoimmune Pancreatitis and Other Organ Involvement Go Kuwata, Terumi Kamisawa
Chapter 54 Cutaneous and Oral Manifestations of Inflammatory Bowel Disease Caroline P. Allen, Susan M. Burge
Chapter 55 Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel Disease Alistair Tindell, Hanna Johnsson, Iain B. McInnes
Part 7 Nutrition
Chapter 56 Nutrition in Inflammatory Bowel Disease Alan L. Buchman
Part 8 Pregnancy, Family Planning and Pediatric Aspects
Chapter 57 Pregnancy and Fertility in Inflammatory Bowel Disease Rebecca Matro, Uma Mahadevan
Chapter 58 Pediatric Aspects of Inflammatory Bowel Disease Brendan Boyle, Jeffrey S. Hyams
Part 9 Surveillance and Prevention
Chapter 59 Management and Prevention of Infectious Diseases in Irritable Bowel Disease Patients Kristine Macartney, Nigel Crawford
Chapter 60 Incidence of Cancer and Screening in Inflammatory Bowel Disease Jimmy K. Limdi, Francis A. Farraye
Chapter 61 Inflammatory Bowel Diseases: How to Identify High Risk Patients Jacques Cosnes, Harry Sokol
Part 10 Patient Perspective and Resources
Chapter 62 Patient Perspective on Inflammatory Bowel Disease Ayesha Williams, Marjorie Merrick
Chapter 63 Patient Resources in Inflammatory Bowel Disease Sanna Lönnfors, Marco Greco
Chapter 1 Environmental Factors in the Epidemiology of Inflammatory Bowel DiseaseMorten H. Vatn
Part 2 Immunobiology
Chapter 2 The Intestinal Immune System in HealthPer Brandtzaeg
Chapter 3 Understanding the Epithelial Barrier in Inflammatory Bowel DiseaseMatthew A. Odenwald, Jerrold R. Turner
Chapter 4 Intestinal Microbiology and Ecology in Crohn's Disease and Ulcerative ColitisDirk Haller, Ludovica F. Butto
Chapter 5 The Immune System in Inflammatory Bowel Disease: Antimicrobial PeptidesCharles L. Bevins
Chapter 6 Vascular Responses to Intestinal InflammationD. Neil Granger, Norman R. Harris
Chapter 7 Immunobiology of Human Dendritic Cells in Inflammatory Bowel DiseaseDaniel C. Baumgart
Chapter 8 Immunobiology of T-Cells in Inflammatory Bowel DiseaseS. Snapper, D. Nguyen, A Biswas
Chapter 9 Immunobiology of B cells in Inflammatory Bowel DiseaseAtsushi Mizoguchi, Atul K. Bhan
Chapter 10 Immune Cells: Monocytes and MacrophagesGerhard Rogler
Chapter 11 Immune Functions of Epithelial Cells in Inflammatory Bowel DiseaseEric L. Campbell, Sean P. Colgan
Chapter 12 Autophagy and Endoplasmic Reticulum StressArthur Kaser
Chapter 13 Matrix MetalloproteinasesPaolo Biancheri, Thomas T. MacDonald
Chapter 14 Paradigm of T-cell Differentiation in Inflammatory Bowel DiseaseTakashi Nagaishi, Mamoru Watanabe
Chapter 15 Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal InflammationCynthia Reinoso Webb, Matthew B. Grisham
Chapter 16 Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel DiseaseJorge O. Múnera, James M. Wells
Part 3 Diagnostic Approach
Chapter 17 Enhanced EndoscopyRalf Kiesslich
Chapter 18 Magnetic Resonance EnterographyPatrik Rogalla, Luis Guimaraes
Chapter 19 Computed Tomography Enterography and Inflammatory Bowel DiseaseJ. G. Fletcher
Chapter 20 Ultrasound in Inflammatory Bowel DiseaseA. Potthoff, C. Agné, M. Gebel
Chapter 21 Laboratory Evaluation, Including Novel Diagnostic MarkersM. Flamant, X. Roblin
Chapter 22 Pathology of Inflammatory Bowel DiseaseNora E. Joseph, Christopher R. Weber
Chapter 23 Objective Assessment of Clinical Disease ActivityEdouard Louis, Catherine Van Kemseke, Catherine Reenaers
Chapter 24 Objective Assessment of Endoscopic Disease Activity and Mucosal HealingBritt Christensen, David T. Rubin
Chapter 25 Evaluation of Quality of Life in Crohn's disease and Ulcerative Colitis: What Is Health-Related Quality of Life?Katrine Carlsen, Pia Munkholm, Johan Burisch
Chapter 26 Evaluation of Health Economics in Inflammatory Bowel DiseaseReena Khanna, Brian G. Feagan
Part 4 Therapy Crohn's Disease
Chapter 27 The Natural History of Inflammatory Bowel DiseaseCharles N. Bernstein
Chapter 28 Conventional Medica Management of Crohn's Disease: SulfasalazineMiquel A. Gassull, Eduard Cabré
Chapter 29 Steroid Therapy for Crohn's DiseaseA. Hillary Steinhart
Chapter 30 Thiopurines in Crohns' disease Adi Lahat, Rami Eliakim
Chapter 31 Conventional Medical Management of Crohn's Disease: MethotrexateGrace Harkin, Laurence Egan
Chapter 32 Adalimumab for the Treatment of Crohn's Disease Remo Panaccione
Chapter 33 Biologic Therapy of Crohn's Disease: CertolizumabAlessandro Armuzzi, Daniela Pugliese
Chapter 34 Biologic Therapy of Crohn's Disease: InfliximabJan-Michael A. Klapproth, Gary R. Lichtenstein
Chapter 35 Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease TreatmentPeter J. Mannon
Chapter 36 Biologic Therapy of Crohn's Disease: Natalizumab, Vedolizumab and anti-MadCAMPieter Hindryckx, Geert D'Haens
Chapter 37 Optimal Management of Fistulizing Crohn's DiseaseBruce Sands, Farhad Peerani
Part 5 Therapy Ulcerative Colitis
Chapter 38 Sulfasalazine and 5-Aminosalicylates for Ulcerative ColitisReena Khanna, John K. Marshall
Chapter 39 Conventional Therapy of Ulcerative Colitis: CorticosteroidsKirstin Taylor, Peter R. Gibson
Chapter 40 Medical Management of Ulcerative Colitis: Conventional Therapy--AzathioprineBarrett G. Levesque, Edward V. Loftus
Chapter 41 Calcineurin Inhibitors in Ulcerative ColitisAndreas Fischer, Daniel C. Baumgart
Chapter 42 Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: InfliximabMindy Lam, Brian Bressler
Chapter 43 Biologic Therapy of Ulcerative Colitis: AdalimumabWalter Reinisch
Chapter 44 Biologic Therapy of Ulcerative Colitis: GolimumabMark A. Samaan, Peter M. Irving
Chapter 45 Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAMSeverine Vermeire
Chapter 46 Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel DiseasePaolo Gionchetti, Carlo Calabrese, Andrea Calafiore, Fernando Rizzello
Chapter 47 Biosimiliars in the Treatment of Inflammatory Bowel DiseaseVivian W. Huang, Richard N. Fedorak
Chapter 48 Step-up vs. Top-down Approach in Crohn's DiseaseChristine Y. Yu, Daniel W. Hommes
Chapter 49 Leucocytapheresis Therapy of Inflammatory Bowel DiseaseTakanori Kanai
Chapter 50 Surgical Management of Crohn's Disease and Ulcerative ColitisRobert R. Cima, John H. Pemberton
Part 6 Extraintestinal Manifestations
Chapter 51 Extraintestinal Manifestations: Autoimmune HepatitisMichael Manns, Nora Schweitzer
Chapter 52 Primary Sclerosing CholangitisRoger W. Chapman, Kate D. Williamson
Chapter 53 Autoimmune Pancreatitis and Other Organ InvolvementGo Kuwata, Terumi Kamisawa
Chapter 54 Cutaneous and Oral Manifestations of Inflammatory Bowel DiseaseCaroline P. Allen, Susan M. Burge
Chapter 55 Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel DiseaseAlistair Tindell, Hanna Johnsson, Iain B. McInnes
Part 7 Nutrition
Chapter 56 Nutrition in Inflammatory Bowel DiseaseAlan L. Buchman
Part 8 Pregnancy, Family Planning and Pediatric Aspects
Chapter 57 Pregnancy and Fertility in Inflammatory Bowel DiseaseRebecca Matro, Uma Mahadevan
Chapter 58 Pediatric Aspects of Inflammatory Bowel DiseaseBrendan Boyle, Jeffrey S. Hyams
Part 9 Surveillance and Prevention
Chapter 59 Management and Prevention of Infectious Diseases in Irritable Bowel Disease PatientsKristine Macartney, Nigel Crawford
Chapter 60 Incidence of Cancer and Screening in Inflammatory Bowel DiseaseJimmy K. Limdi, Francis A. Farraye
Chapter 61 Inflammatory Bowel Diseases: How to Identify High Risk PatientsJacques Cosnes, Harry Sokol
Part 10 Patient Perspective and Resources
Chapter 62 Patient Perspective on Inflammatory Bowel DiseaseAyesha Williams, Marjorie Merrick
Chapter 63 Patient Resources in Inflammatory Bowel DiseaseSanna Lönnfors, Marco Greco