In order to improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies includingsome based on the molecular and genetic phenotype of the disease. This volume will ¿provide a comprehensive review of these new discoveries in one singular text, which will help move the field forward.
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