Detection Methods for Cynobacterial toxins (eBook, PDF)

Redaktion: Codd, G A; Potter, E.; Keevil, C W; Jefferies, T M

• Format: PDF

Produktbeschreibung

Cyanobacteria, or blue-green algae, commonly occur in a variety of water types throughout the world. A variable, but, high proportion of the cyanobacterial blooms and scums, which can develop annually in lakes, reservoirs, canals and slow-flowing rivers, contain potent toxins. Although animal poisonings and human health problems associated with the ingestion of, or contact with, cyanobacterial scums have long been recognized, a developing understanding of the health hazards posed by the toxins requires that reliable, sensitive, specific and convenient methods are available for their detection and quantification.

Detection methods for cynobacterial toxins looks at the application of biological, toxicological, biochemical and physicochemical techniques in studies of cyanobacterial toxins and at experimental methods that have identified at least 50 cyanobacterial compounds toxic to vertebrates.

Academics, public health bodies, environmental protection agencies and water companies are all involved in monitoring cyanobacterial levels and effects, and this book will help to ensure that their research is not duplicated, is standardized and comparable, and that optimal progress can be made in an important area that is still in its developing stages.

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 202
• Erscheinungstermin: 1. Januar 1994
• Englisch
• ISBN-13: 9781845698164
• Artikelnr.: 40693342

Inhaltsangabe

Health problems from exposure to cyanobacteria and proposed safety
guidelines for drinking and recreational water; An epidemiological critique
of reports of human illness associated with cyanohacteria; Cyclic peptide
hepatotoxins from fresh water cyanobacteria water blooms collected in the
river dnieper reservoirs and other water bodies from the European part of
Russia; Structural analysis of cyanobacterial toxins; Determinations of
anatoxin-a, homoanatoxin and propylanatoxin in cyanobacterial extracts by
HPLC, GC-mass spectrometry and capillary electrophoresis;
Enantiomer-specific analysis of homoanatoxin-a. a cyanophyte neurotoxin;
Neurotoxins from Australian Anabaena; The analysis of microcystin-LR in
water: Application in water treatment studies; The analysis of microcystins
in raw and treated water; Application of HPLC and mass spectrometry (MALDI)
to the detection and identification of toxins from microcystis,
oscillatoria and aphanizomenon from several freshwater reservoirs; Routes
of intoxication; Testing of toxicity in cyanobacteria by cellular assays; A
sensitive bioscreen for detection of cyclic peptide toxins of the
microcystin class; The inhibition of protein phosphatases by toxins:
Implications for health and an extremely sensitive and rapid bioassay for
toxin detection; Detection of hepatotoxins by protein phosphatase
inhibition assay: advantages, pitfalls and anomalies; Alternatives to the
mouse bioassay for cyanobacterial toxicity assessment; Evaluation of assay
methods for the determination of cyanobacterial hepatotoxicity; The role of
synthetic chemistry in the production of standards for toxin analysis;
Sources of uncertainty in assessing the health risk of cyanobacterial
blooms in drinking water supplies; Standing committee of analysts; Toxic
cyanobacteria (blue-green algae) in Portuguese freshwaters; Screening of
cyanobactenal toxins in microcystis aeruginosa collected from blooms and
cultures; Toxicity studies with blue-green algae from Flemish reservoirs;
Cases of cyanobacterial toxicoses on Swiss alpine pastures; Biological and
economic significance of benthic cyanobacteria in two Scottish highland
lochs; First results on the occurrence of microcystin-LR in Berlin and
Brandenburg lakes; Variation of cyanobacterial hepatotoxins in Finland; A
method for the detection of cyanobacterial peptide toxins by HPLC; Release
and degradation of microcystin during a microcystis aeru bloom in a
freshwater reservoir; Characterization of hepatotoxins from freshwater
oscillatoria species: Variation in toxicity and temporal expression;
Expression of cyanotoxins in environmental biomass containing species of
oscillatoria; A simple and rapid method for extraction of toxic peptides
from cyanobacteria; Phosphatase assay as a determinant of hepatotoxin
toxicity; Detection of cyanobacterial (blue-green algal) peptide toxins by
protein phosphatase inhibition; Investigation of the solution conformation
of microcystins-LR and -RR by high field nuclear magnetic resonance; The
tandem mass spectrometry of nodularin, microcystins and other cyclic
peptides.