Doctoral Thesis / Dissertation from the year 2020 in the subject Health - Children and adolescents, Clark University, language: English, abstract: This study seekts to determine the factors associate with uptake of human papilloma virus vaccine in Bukomansimbi Sub-County, Bukomansimbi district. The ministry of health Uganda adopted WHO guideline on routine immunization which was included in UNEPI and ensures that all girls at the age 11-15 to receive full dose in order to have full protection how ever since the introduction of the HPV vaccine in November 2015. There has been low uptake of the vaccine in Uganda with 33,6% prevalence among women combined with low screening uptake , this lead country being one of the highest cervical cancer with incidence rate of 47,5 per 100,000 per year. At Bukomansimbi Sub County the target population of girl to be vaccinated according to the Bukomansimbi medical center records was 200 girls in the age bracket, many girls do not complete their doses as shown by the vaccination records book, girls normally hide a way during the time of vaccination and parents discourage their girls from receiving the HPV vaccine due to ignorance. Since infection by HPV is the leading predisposing factor and cause of cancers of the cervix, vagina, and vulva in women this leads to the high expenditures for the family to spend on medical expenses, government on the other hand loses too much to treat.