Developmental and Reproductive Toxicology (eBook, ePUB)

A Practical Approach
Redaktion: Hood, Ronald D

• Format: ePub

Produktbeschreibung

Originally titled Handbook of Developmental Toxicology, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition is a guide for developmental and reproductive toxicologists. Completely revised and updated, this new editionnew chapters covers genomics/proteomics, endocrine disruptors, testing for male and female reproductive toxicity, data interpretation in developmental and reproductive toxicity testing, nonclinical juvenile toxicity testing, and the FDA perspective on risk assessment. It includes material on postnatal developmental milestones and extensive glossaries of developmental defect terminology. Practical and informative, the book bridges the gap between theory and application. It contains insights gained from hands-on experience and gathers information scattered throughout the literature, along with previously unpublished information, into one reference.

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Produktdetails

• Verlag: Taylor & Francis
• Erscheinungstermin: 19. April 2016
• Englisch
• ISBN-13: 9781040057414
• Artikelnr.: 72531826

Autorenporträt

Ronald D. Hood is a Toxicology Consultant at Ronald D. Hood & Associates and works at the University of Alabama, Tuscaloosa, USA.

Inhaltsangabe

PRINCIPLES AND MECHANISMS. Principles of Developmental Toxicology.
Mechanisms of Developmental Toxicology. Pathogenesis of Abnormal
Development. Maternally-Mediated Effects on Development.
Paternally-Mediated Effects on Development. Comparative Embryology. HAZARD
ASSESSMENT. Developmental Toxicity Testing - Single and Multiple Generation
Test Methodology. Nonclinical Juvenile Toxicity Testing -- Methodology and
Data Evaluation. Testing for Reproductive Toxicity in the Male and Female
and Evaluation of the Data. Endocrine Disruption - Testing and Data
Evaluation. Role of Xenobiotic Metabolism in Developmental Toxicity.
Toxicokinetics. Cellular, Biochemical, and Molecular Techniques. Genomics
and Proteomics. In Vitro Mechanistic Studies. Statistical Analysis. Quality
Control - GLP for Toxicologists. Regulatory Test Guidelines. Epidemiologic
Techniques in Development and Reproductive Toxicology. Risk Assessment -
EPA Approach. Risk Assessment - FDA Approach. Appendices.