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Diabetes and the Kidney provides endocrinologists and nephrologists of all levels with expert clinical diagnosis and management guidance for this extremely common diabetic complication. Practical and accessible, chapters contain text features such as case histories, potential pitfall boxes, key points, management algorithms, and useful weblinks to fully engage the reader and provide expert guidance to help clinicians best manage their patients. In addition, all relevant international society guidelines and recommendations are fully included. After an initial analysis of the epidemiology and…mehr
Diabetes and the Kidney provides endocrinologists and nephrologists of all levels with expert clinical diagnosis and management guidance for this extremely common diabetic complication. Practical and accessible, chapters contain text features such as case histories, potential pitfall boxes, key points, management algorithms, and useful weblinks to fully engage the reader and provide expert guidance to help clinicians best manage their patients. In addition, all relevant international society guidelines and recommendations are fully included. After an initial analysis of the epidemiology and pathogenesis of kidney complications in diabetes, it quickly moves on to the following core sections: * Special Situations, Risk factors and Complications - examining diabetic nephropathy in relation to each other diabetic complication, ie cardiovascular disease * Prevention and Therapy - focusing on the most up to date information regarding prevention, diagnosis, treatment, and management of kidney disease in diabetes. Expertly edited, and with contributions from an experienced international team, Diabetes and Kidney Disease will be the perfect tool to consult when managing diabetic patients with associated kidney problems.
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Autorenporträt
Gunter Wolf is Professor and Chairman, Department for Internal Medicine III (Nephrology, Rheumatology, Osteology, Endocrinology and Diabetology) at the Friedrich Schiller University in Jena, Germany. Professor Wolf is well known both in Europe and America, and is involved in many editorial boards and journals such as Kidney International, Journal American Society of Nephrology, European Journal of Clinical Investigation, Hypertension and the renal section of the American Journal of Physiology. Professor Wolf is also the author of Obesity and the Kidney, Karger, 2006.
Inhaltsangabe
Contributors, vii Preface, x Part I Introduction and Pathophysiology 1 History of diabetic nephropathy: a personal account, 3 Eberhard Ritz 2 Epidemiology of chronic kidney disease in diabetes, 14 Andrea Icks and Michael Koch 3 Genetic risk factors for diabetic nephropathy, 29 Carsten A. Böger and Peter R. Mertens 4 Pathophysiology of diabetic nephropathy, 45 Ivonne Loeffler 5 Histology of human diabetic nephropathy, 62 Kerstin Amann and Christoph Daniel 6 Natural history and diagnosis of diabetic kidney disease, 70 Bethany Karl and Kumar Sharma Part II Special Situations, Risk Factors and Complications 7 Cardiovascular disease in diabetic nephropathy: pathophysiology and treatment, 85 Martin Busch 8 Statin therapy in patients with diabetic nephropathy, 101 Christoph Wanner 9 Diabetes mellitus, bone and kidney, 116 Thomas Neumann and Gabriele Lehmann 10 Diabetes, pregnancy and the kidney, 129 Helmut Kleinwechter and Ute Schäfer-Graf 11 Diabetic nephropathy in children, 143 Kai D Nüsken and Jörg Dötsch 12 Diabetes, the kidney and retinopathy, 153 Hans-Peter Hammes Part III Prevention and Therapy 13 Reducing progression of diabetic nephropathy by antihyperglycemic treatment, 171 Christoph Hasslacher 14 Dosage of antihyperglycemic drugs in patients with renal insuffi ciency, 186 Alexander Sämann and Ulrich A. Müller 15 Reducing progression of diabetic nephropathy by antihypertensive treatment, 202 Anita Hansen, Ivo Quack and Lars Christian Rump 16 Treatment of the patient with end-stage diabetic nephropathy, 215 Muriel Ghosn and Fuad N. Ziyadeh 17 Combined pancreas and kidney transplantation or kidney alone transplantation for patients with diabetic nephropathy, 232 Hermann J. Kissler, Christiane Rüster and Utz Settmacher Index, 253 Color plate section can be found facing page 54
Contributors, vii Preface, x Part I Introduction and Pathophysiology 1 History of diabetic nephropathy: a personal account, 3 Eberhard Ritz 2 Epidemiology of chronic kidney disease in diabetes, 14 Andrea Icks and Michael Koch 3 Genetic risk factors for diabetic nephropathy, 29 Carsten A. Böger and Peter R. Mertens 4 Pathophysiology of diabetic nephropathy, 45 Ivonne Loeffler 5 Histology of human diabetic nephropathy, 62 Kerstin Amann and Christoph Daniel 6 Natural history and diagnosis of diabetic kidney disease, 70 Bethany Karl and Kumar Sharma Part II Special Situations, Risk Factors and Complications 7 Cardiovascular disease in diabetic nephropathy: pathophysiology and treatment, 85 Martin Busch 8 Statin therapy in patients with diabetic nephropathy, 101 Christoph Wanner 9 Diabetes mellitus, bone and kidney, 116 Thomas Neumann and Gabriele Lehmann 10 Diabetes, pregnancy and the kidney, 129 Helmut Kleinwechter and Ute Schäfer-Graf 11 Diabetic nephropathy in children, 143 Kai D Nüsken and Jörg Dötsch 12 Diabetes, the kidney and retinopathy, 153 Hans-Peter Hammes Part III Prevention and Therapy 13 Reducing progression of diabetic nephropathy by antihyperglycemic treatment, 171 Christoph Hasslacher 14 Dosage of antihyperglycemic drugs in patients with renal insuffi ciency, 186 Alexander Sämann and Ulrich A. Müller 15 Reducing progression of diabetic nephropathy by antihypertensive treatment, 202 Anita Hansen, Ivo Quack and Lars Christian Rump 16 Treatment of the patient with end-stage diabetic nephropathy, 215 Muriel Ghosn and Fuad N. Ziyadeh 17 Combined pancreas and kidney transplantation or kidney alone transplantation for patients with diabetic nephropathy, 232 Hermann J. Kissler, Christiane Rüster and Utz Settmacher Index, 253 Color plate section can be found facing page 54
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