Diabetic Neuropathy (eBook, PDF)

Clinical Management

• Format: PDF

Produktbeschreibung

In this newly updated, second edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. These authoritative contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy and highlight the relatively unknown features of neuropathy that can significantly impact a patient's life. Comprehensive, up-to-date bibliographies at the end of each chapter provide an opportunity for the interested physician to gain a more detailed picture of a particular topic.

Produktdetails

• Verlag: Humana Press
• Erscheinungstermin: 1. Februar 2008
• Englisch
• ISBN-13: 9781597453110
• Artikelnr.: 37354034

Autorenporträt

Aristides Veves, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA / Rayaz A. Malik, Manchester Royal Infirmary, Manchester, UK

Inhaltsangabe

Historical Aspects of Diabetic Neuropathies.- The Epidemiology of Diabetic Neuropathy.- Genomics of Diabetic Neuropathy.- Transgenic and Gene Knockout Analysis of Diabetic Neuropathy.- Hyperglycemia-Initiated Mechanisms in Diabetic Neuropathy.- Effectors—Sonic Hedgehog and p38 Mitogen-Activated Protein Kinase.- Neuronal and Schwann Cell Death in Diabetic Neuropathy.- Metabolic-Functional-Structural Correlations in Somatic Neuropathies in the Spontaneously Type 1 and Type 2 Diabetic BB-Rats.- Experimental Diabetic Autonomic Neuropathy.- Spinal Cord.- Diabetic Encephalopathy.- Microangiopathy, Diabetes, and the Peripheral Nervous System.- Pathogenesis of Human Diabetic Neuropathy.- Clinical Features of Diabetic Polyneuropathy.- Micro- and Macrovascular Disease in Diabetic Neuropathy.- Clinical Diagnosis of Diabetic Neuropathy.- Punch Skin Biopsy in Diabetic Neuropathy.- Aldose Reductase Inhibitors for the Treatment of Diabetic Neuropathy.- Other Therapeutic Agents for the Treatment of Diabetic Neuropathy.- Pathophysiology of Neuropathic Pain.- Treatment of Painful Diabetic Neuropathy.- Focal and Multifocal Diabetic Neuropathy.- Hypoglycemia and the Autonomic Nervous System.- Cardiovascular Autonomic Neuropathy.- Postural Hypotension and Anhidrosis.- Gastrointestinal Syndromes Due to Diabetes Mellitus.- Genitourinary Complications.- Management of Diabetic Foot Complications.

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Historical Aspects of Diabetic Neuropathies.- The Epidemiology of Diabetic Neuropathy.- Genomics of Diabetic Neuropathy.- Transgenic and Gene Knockout Analysis of Diabetic Neuropathy.- Hyperglycemia-Initiated Mechanisms in Diabetic Neuropathy.- Effectors-Sonic Hedgehog and p38 Mitogen-Activated Protein Kinase.- Neuronal and Schwann Cell Death in Diabetic Neuropathy.- Metabolic-Functional-Structural Correlations in Somatic Neuropathies in the Spontaneously Type 1 and Type 2 Diabetic BB-Rats.- Experimental Diabetic Autonomic Neuropathy.- Spinal Cord.- Diabetic Encephalopathy.- Microangiopathy, Diabetes, and the Peripheral Nervous System.- Pathogenesis of Human Diabetic Neuropathy.- Clinical Features of Diabetic Polyneuropathy.- Micro- and Macrovascular Disease in Diabetic Neuropathy.- Clinical Diagnosis of Diabetic Neuropathy.- Punch Skin Biopsy in Diabetic Neuropathy.- Aldose Reductase Inhibitors for the Treatment of Diabetic Neuropathy.- Other Therapeutic Agents for the Treatment of Diabetic Neuropathy.- Pathophysiology of Neuropathic Pain.- Treatment of Painful Diabetic Neuropathy.- Focal and Multifocal Diabetic Neuropathy.- Hypoglycemia and the Autonomic Nervous System.- Cardiovascular Autonomic Neuropathy.- Postural Hypotension and Anhidrosis.- Gastrointestinal Syndromes Due to Diabetes Mellitus.- Genitourinary Complications.- Management of Diabetic Foot Complications.

Rezensionen

From the reviews of the second edition:

"This comprehensive review of diabetic neuropathy covers pathophysiology, state-of-the-art diagnosis and treatment, and future basic science and clinical trial directives. ... I recommend this book to graduate students, researchers, clinical trial designers, librarians, and neurologists and endocrinologists with a special interest in diabetic neuropathy and diabetic microvascular complications. ... This is an outstanding resource on diabetic neuropathy as well as diabetic microvascular complications in general. It is certainly a very useful contribution to the scientific literature." (Kourosh Rezania, Doody's Review Service, December, 2007)

"This is the second updated edition of a comprehensive text covering in 28 chapters the majority of neurological complications occurring in diabetes mellitus. Addressed to adult diabetologists and practitioners, though neuropathy may also be diagnosed in adolescent patients." (Pediatric Endocrinology Reviews, Vol. 5 (3), 2008)

"This comprehensive textbook provides general practitioners details about the latest techniques for the clinical management of diabetic neuropathy. ... Each chapter includes a summary, a list of key words, and an extensive list of references. A subject index concludes the volume." (National Institute of Diabetes and Digestive Kidney Diseases Reference Collection, May, 2008)

"The second edition is intended for the general practitioner and includes contributions from various leading medical specialists and researchers in this field. The book includes new chapters that provide greater detail on the pathophysiology of diabetic neuropathy, while expanding its discussion of the diagnosis and management of the various presentations of the disease. ... the reader should appreciate the efforts made by the authors and editors to provide the most current data from researchers and experts in this area." (Stephanie C. Wu, Journal ofthe American Podiatric Medical Association, Vol. 98 (3), May/June, 2008)

"This book comprehensively reviews various aspects of diabetic neuropathies. ... The book is nicely edited and all chapters are well written in easy-to-understand English. ... Most chapters are very useful for most physicians involved in the care for diabetic patients. This book should appear on the bookshelf of all those clinicians and researchers involved in diabetic neuropathy, and is of particular importance to endocrinologists, general internists and neurologists." (Jan De Bleecker, Acta Clinica Belgica, Vol. 63 (3), 2008)