Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer (eBook, ePUB)

Redaktion: Kumar, Ashok; Khan, Frsc; Tiwari, Shikha; Arya, Neha

• Format: ePub

Produktbeschreibung

Early diagnosis of HNSCC can cause improved treatment, treatment response rates and reduction in mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for diagnosis, prognosis, and treatment of HNSCC. It encompasses various miRNA-based point of care diagnostics and drug delivery systems for HNSCC along with the information on the clinical trials of miRNAs for improved clinical outcomes in HNSCC patients. The book provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. This book will help scientists and clinicians to win the battle against HNSCC. - Covers the role of the tumor microenvironment in head and neck cancer - Provides information on oncogenic and tumor suppressor miRNAs dysregulated in HNSCC patients - Elucidates the role of miRNAs in metastasis, recurrence, and chemoresistance in HNSCC - Includes the current state-of-art in miRNA-based clinical trials for head

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 270
• Erscheinungstermin: 25. Juli 2024
• Englisch
• ISBN-13: 9780443159695
• Artikelnr.: 72251529

Inhaltsangabe

1. Epidemiology, pathology and genomic topography of head and neck cancer
2. Association of human papillomavirus with head and neck cancer
3. microRNA regulation of different subtypes of head and neck cancer
4. Oncogenic and tumor suppressor microRNAs in head and neck cancer
5. Epigenetic regulation of head and neck cancer by microRNAs
6. Association of genetic variations in microRNAs with susceptibility to
head and neck cancer
7. Role of microRNAs in metastasis, recurrence and chemo-radiation
resistance of head and neck cancer
8. Regulation of head and neck tumor microenvironment by microRNAs
9. Genome wide discovery and prediction of microRNA-based biomarkers in
head and neck squamous cell carcinoma
10. Computational modelling for identification of miRNAs as diagnostic and
prognostic biomarkers for head and neck cancer
11. Development of microRNA as diagnostic markers in head and neck cancer
12. Development of microRNA as prognostic markers in head and neck cancer
13. Exosomal microRNA for diagnosis and prognosis of head and neck cance
14. MicroRNA expression profiling for disease progression assessment
15. MicroRNA-based point-of-care devices for diagnosis and prognosis of
head and neck cancer
16. Therapeutic role of microRNAs in management of head and neck cancer
17. miRNAs in the management of nutritional deficiencies and cachexia in
Head and Neck Cancer patients
18. MicroRNA-based nanomedicine for treatment of head and neck cancer
19. MicroRNA-based clinical trials for head and neck cancer