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Inhaltsangabe
I: Cell Biology of Diastole.- 1. Cellular Mechanisms of Relaxation: Lessons From Frogs, Birds, and Mammals.- 2. Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation.- 3. Calcium and Cardiac Relaxation.- 4. Variable Calcium Sensitivity of the Mammalian Cardiac Contractile System.- 5. Is Ischemic Contracture Preceded by a Rise in Free Calcium?.- 6. The Effect of Regional Myocardial Heterogeneity on the Economy of Isometric Relaxation.- 7. Functional Sequelae of Diastolic Sarcoplasmic Reticulum Ca2+ Release in the Myocardium.- II: Physiologic Modifiers of Relaxation in Experimental Models.- 8. Hypoxia and Relaxation.- 9. Ischemic/Hypoxic and Reperfusion/Reoxygenation Contractures: Mechanisms.- 10. Load Dependence of Relaxation.- 11. The Effects of Cardiac Hypertrophy on Intracellular Ca2+ Handling.- III: Evaluation of Relaxation and Compliance in the Intact Heart.- 12. Diastolic Myocardial Mechanics and the Regulation of Cardiac Performance.- 13. Evaluation of Time Course of Left Ventricular Isovolumic Relaxation in Man.- 14. Loading Conditions and Left Ventricular Relaxation.- 15. Influence of Pressure and Volume Overload on Diastolic Compliance.- 16. Influence of the Pericardium on Diastolic Compliance.- 17. Implications of Pericardial Pressure for the Evaluation of Diastolic Dysfunction.- 18. Comparative Effects of Ischemia and Hypoxia on Ventricular Relaxation in Isolated Perfused Hearts.- 19. Effects of Hypoxia on Relaxation of the Hypertrophied Ventricle.- 20. Relaxation and Diastolic Distensibility of the Regionally Ischemic Left Ventricle.- IV: Clinical Disorders of Diastolic Relaxation and Compliance.- 21. Altered Diastolic Distensibility During Angina Pectoris.- 22. Diastolic Function During Exercise-Induced Ischemia in Man.- 23. Left VentricularFilling in Ischemic and Hypertrophic Heart Disease.- 24. Regional Diastolic Dysfunction in Coronary Artery Disease: Clinical and Therapeutic Implications.- 25. Ejection, Filling, and Diastasis During Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function.- 26. Diastolic Ventricular Function in Primary and Secondary Hypertrophy: The Influence of Verapamil.- 27. Failure of Inactivation of Hypertrophied Myocardium: A Cause of Impaired Left Ventricular Filling in Hypertrophic Cardiomyopathy and Aortic Stenosis.
I: Cell Biology of Diastole.- 1. Cellular Mechanisms of Relaxation: Lessons From Frogs, Birds, and Mammals.- 2. Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation.- 3. Calcium and Cardiac Relaxation.- 4. Variable Calcium Sensitivity of the Mammalian Cardiac Contractile System.- 5. Is Ischemic Contracture Preceded by a Rise in Free Calcium?.- 6. The Effect of Regional Myocardial Heterogeneity on the Economy of Isometric Relaxation.- 7. Functional Sequelae of Diastolic Sarcoplasmic Reticulum Ca2+ Release in the Myocardium.- II: Physiologic Modifiers of Relaxation in Experimental Models.- 8. Hypoxia and Relaxation.- 9. Ischemic/Hypoxic and Reperfusion/Reoxygenation Contractures: Mechanisms.- 10. Load Dependence of Relaxation.- 11. The Effects of Cardiac Hypertrophy on Intracellular Ca2+ Handling.- III: Evaluation of Relaxation and Compliance in the Intact Heart.- 12. Diastolic Myocardial Mechanics and the Regulation of Cardiac Performance.- 13. Evaluation of Time Course of Left Ventricular Isovolumic Relaxation in Man.- 14. Loading Conditions and Left Ventricular Relaxation.- 15. Influence of Pressure and Volume Overload on Diastolic Compliance.- 16. Influence of the Pericardium on Diastolic Compliance.- 17. Implications of Pericardial Pressure for the Evaluation of Diastolic Dysfunction.- 18. Comparative Effects of Ischemia and Hypoxia on Ventricular Relaxation in Isolated Perfused Hearts.- 19. Effects of Hypoxia on Relaxation of the Hypertrophied Ventricle.- 20. Relaxation and Diastolic Distensibility of the Regionally Ischemic Left Ventricle.- IV: Clinical Disorders of Diastolic Relaxation and Compliance.- 21. Altered Diastolic Distensibility During Angina Pectoris.- 22. Diastolic Function During Exercise-Induced Ischemia in Man.- 23. Left VentricularFilling in Ischemic and Hypertrophic Heart Disease.- 24. Regional Diastolic Dysfunction in Coronary Artery Disease: Clinical and Therapeutic Implications.- 25. Ejection, Filling, and Diastasis During Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function.- 26. Diastolic Ventricular Function in Primary and Secondary Hypertrophy: The Influence of Verapamil.- 27. Failure of Inactivation of Hypertrophied Myocardium: A Cause of Impaired Left Ventricular Filling in Hypertrophic Cardiomyopathy and Aortic Stenosis.
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