Akhileshwar Kumar Srivastava, Divya Singh, Rajesh Kumar Singh

Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Phytochemicals and derivatives have become promising alternatives to increase treatment potential in cancer patients with minimal side effects. Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery system in cancer treatment.

Several nanotechnological methods are followed to enhance drug solubility, sustainability, bioavailability and gastrointestinal permeability of these phytochemicals. The advanced field of drug-delivery systems explains that combination therapy for cancer treatment has important benefits over mono-delivery therapeutics. Natural compounds, because of their biobased origin, have drawn higher attention than synthetic drugs. Synthesis of nano-phytomedicines has impacted the bioavailability of phytochemicals. Novel formulations have been synthesized loaded with phytochemicals and have revealed extraordinary results in treatment of various cancers.

Current understanding of the relevant information presented in Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers, who want to work in the areas of drug development targeting phytochemicals for cancer therapy

• Explains the significance of phytochemicals in cancer therapy, along with their pharmacologic action
• Elucidates the importance of various phytochemicals in cancer therapy
• Explains the emerging need of drug-delivery system for plant metabolites
• Deciphers the various drug-delivery systems for phytomedicines involved in cancer treatments
• Describes the crucial role of nanotechnology in the development of drug-delivery systems for anticancer phytochemicals
• Explores the challenges associated with developing drug-delivery systems for phytochemicals to cure cancer

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 320
• Erscheinungstermin: 7. November 2023
• Englisch
• ISBN-13: 9780443159619
• Artikelnr.: 69354719

Autorenporträt

Dr. Akhileshwar Kumar Srivastava works as a Research Associate (ICMR) in CSIR-Central Food Technological Research Institute, Mysore, India. In his eight years of research, he has published approximately 20 research articles and book chapters in international and national journals of repute. His research specialization is primarily in the area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology-associated targeting cancer diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, United States on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel. He is also a life member fellow in Indian Science Congress and Agriculture, Nutrition and Health Academy, United Kingdom.Divya Singh is presently working as Scientist-B in Department of Mulberry Physiology, CSRTI, Mysore, India. Her research specialization is primarily in genetics, proteomics, metabolomics, toxicology, bioinformatics and molecular biological evaluation in various in vivo and in vitro plant models to elucidate the physiological changes and evaluate the DNA damage potency. In her 11 years of research experiences, she has published 8-peer reviewed publications, two books (1 edited and 1 authored) including 6 book chapters and several meeting presentations at local and international scientific meetings.Dr. Rajesh Kumar Singh is currently working as a Research Associate in Banaras Hindu University. His research focus is pharmacognosy, reverse pharmacology, drug design and discovery, extraction & isolation of natural products, cell culture, and handling of different rodents. He has published several research articles in reputable journals over the course of his career. At present, he is involved in developing an Indian origin cell line and screening drugs of natural origin for the treatment of gallbladder cancer.

Inhaltsangabe

1. Significance of phytochemicals in cancer therapy
2. Emerging need of delivery systems for plant metabolites
3. Phytosome: A promising drug-delivery system for cancer therapy
4. Exosome-based delivery systems for natural compounds in cancer therapy
5. Potential implications of ethosomes and transethosomes to deliver
phytomedicine in cancer treatment
6. Chitosan-based drug delivery of plant metabolites for the treatment of
breast cancer
7. Sporopollenin-based targeted drug delivery system for gastrointestinal
cancer
8. Nanotechnology based delivery system for phytochemicals in cancer
therapy
9. Delivery system of phenolic compounds for the treatment of lung cancer
10. Advancement in drug delivery systems of curcumin for cancer
chemoprevention
11. Drug delivery system for saponins in cancer treatments
12. Administration of plant-derived terpenoids in cancer management
13. Therapeutic role of essential oils in malignancies through drug
delivery mechanisms
14. Development of codelivery system for phytochemicals and targeted siRNA
in cancer therapy
15. Future challenges of drug-delivery systems for phytochemicals in cancer
management