Drug Repurposing in Cancer Therapy (eBook, ePUB)

Approaches and Applications
Redaktion: To, Kenneth K. W.; Cho, William C. S.

• Format: ePub

Produktbeschreibung

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy.

Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource.

• Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research
• Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences
• Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 458
• Erscheinungstermin: 29. Juli 2020
• Englisch
• ISBN-13: 9780128199039
• Artikelnr.: 61689608

Inhaltsangabe

1. Drug repurposing for cancer therapydan introduction2. A ligand-centric
approach to identify potential drugs for repurposing: case study with
aurora kinase inhibitors3. Machine learning strategies for identifying
repurposed drugs for cancer therapy4. Unveiling potential anticancer drugs
through in silico drug repurposing approaches5. Increasing opportunities of
drug repurposing for treating breast cancer by the integration of
molecular, histological, and systemic approaches6. The success story of
drug repurposing in breast cancer7. A personalized medicine approach to
drug repurposing for the treatment of breast cancer molecular subtypes8.
Successful stories of drug repurposing for cancer therapy in hepatocellular
carcinoma9. Stories of drug repurposing for pancreatic cancer
treatmentdPast, present, and future 10. Animal models and in vivo
investigations for drug repurposing in lung cancer11. Identification of
chemosensitizers by drug repurposing to enhance the efficacy of cancer
therapy12. Drugs repurposed to potentiate immunotherapy for cancer
treatment13. Nanoparticle-based formulation for drug repurposing in cancer
treatment14. Nanotechnological approaches in cancer: the role of celecoxib
and disulfiram15. Clinical trials on combination of repurposed drugs and
anticancer therapies