Epigenetics and Metabolomics (eBook, ePUB)

Redaktion: Agrawala, Paban K.; Rana, Poonam

• Format: ePub

Produktbeschreibung

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare.

• Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research
• Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others
• Provides guidance in epigenomics and metabolomic research methodology

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 476
• Erscheinungstermin: 25. August 2021
• Englisch
• ISBN-13: 9780323856539
• Artikelnr.: 62500665

Inhaltsangabe

1. Metabolomics techniques: A brief update
2. Integration of epigenomics and metabolomics: From biomarkers discovery
to personalized medicine
3. Aging-associated changes in metabolic regulation of epigenetic
modifications and gene expression
4. Epigenetic and metabolic changes in traumatic brain injury
5. Metabolic regulation in urological tumors: Interplay with epigenetics
and epitranscriptomics
6. Multiomics approach for precision wellness
7. Oncogene: An epigenetic regulation
8. Epigenetic regulations in gastrointestine: Implications on sensitivity
to ionizing radiation, inflammatory diseases, and cancer development
9. Epigenetics of epithelial to mesenchymal transition (EMT) in cancer
10. Nutrients seminal role in the development and epigenetic reprogramming
during the first 1000 days of life
11. Epigenetic mechanisms of hepatocellular carcinoma progression:
Potential therapeutic opportunities
12. Translational epigenetics in neurodegenerative diseases
13. Host-epigenetics-microbiota: A tripartite interaction in health and
disease
14. Epigenetics in cardiovascular complications
15. Epigenetics and viral infectious diseases
16. Metabolic profiling leading to clinical phenomics: From bench to
bedside
17. Epigenetic insights for wound healing mechanism
18. Role of metabolomics to investigate combined effect of radiation and
burn
19. Advances and prospects of epigenetics in plants