Epigenetic changes are essential to normal development, but these changes can also cause problems, such as disabling tumor-suppressing genes, making it an important avenue of research in the pharmaceutical industry. Presenting contributions from international experts, this text offers a comprehensive overview of epigenetics, both in normal functions and disease states. Addressing both theoretical and methodological issues, it discusses cell biology and the role of epigenetics in human, animal, and plant diseases; DNA methylation inhibitors; histone modifications; epigenomics; and the impact of diet and nutrition.
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