Epilepsy and Brain Tumors (eBook, ePUB)

Redaktion: Newton MD in Oncology-Neurosurgery, Herbert B.; Maschio, Marta

• Format: ePub

Produktbeschreibung

Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously - a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues.

• Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors
• Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more
• Chapters authored and edited by leaders in the field around the globe - the broadest, most expert coverage available

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 292
• Erscheinungstermin: 6. März 2015
• Englisch
• ISBN-13: 9780124171268
• Artikelnr.: 42540304

Autorenporträt

Dr. Newton is currently the Director of the Neuro-Oncology Center and CNS Oncology Program at the Advent Health Cancer Institute and Advent Health Orlando Campus. He recently retired as Professor of Neurology and Neurosurgery at the Ohio State University Medical Center and the James Cancer Hospital, and was the holder of the Esther Dardinger Endowed Chair in Neuro-Oncology. He trained in Neuro-Oncology with Drs. Jerome Posner and William Shapiro at Memorial Sloan-Kettering Cancer Center in New York, and since then had been in academic Neuro-Oncology for over 25 years. He has published more than 220 peer-reviewed articles and book chapters, and is the Chief Editor or Co-Editor of ten textbooks in the field of Neurology and Neuro-Oncology. In addition, he has been listed as a Best Doctor (Neurology) and Top Doctor for Cancer (Neuro-Oncology) for the past 18 years.

Inhaltsangabe

1. Brain Tumor-Related Epilepsy: Introduction and Overview - Marta Maschio and Herbert B. Newton
2. Overview of Epidemiology, Pathology, and Treatment of Primary Brain Tumors - Herbert B. Newton and Jose Javier Otero
3. Overview of Epidemiology, Pathology, and Treatment of Metastatic Brain Tumors - Herbert B. Newton and Jose Javier Otero
4. Supportive Care of Brain Tumor Patients - Herbert B. Newton and Leslie Ray
5. Brain Tumor-Related Epilepsy in Children - Jonathan Lopez
6. Mechanisms of Focal Epileptogenesis - Marco De Curtis
7. Pathophysiology of brain tumor-related epilepsy - Andrea Salmaggi, Tiziana Granata, and Andrea Rigamonti
8. The Neurophysiology of Central Nervous System Tumors - Jesse W. Mindel, Herbert B. Newton, and J. Layne Moore
9. Surgical Treatment for Epilepsy - Ali Rezai
10. Clinical Evaluation of Epilepsy in the Brain Tumor Patient - Herbert B. Newton and Marta Maschio
11. Antiepileptic Drugs: 1st Generation - Sheri Cotterman-Hart
12. Antiepileptic Drugs: 2nd and 3rd Generation - Sheri Cotterman-Hart
13. Antiepileptic Drugs and Brain Tumor Patients - Marta Maschio, Herbert B. Newton, and Leslie Ray
14. Clinical Approach to BT-Related Epilepsy - Marta Maschio and Herbert B. Newton
15. Neuropsychology of BTRE - Marta Maschio and Loredana Dinapoli
16. Cognitive Rehabilitation in Patients with BTRE - Marta Maschio and Loredana Dinapoli
17. Social Cost of Brain Tumor-Related Epilepsy - Marta Maschio and Francesco Paladin

Rezensionen

"This is an outstanding current review of epilepsy related to brain tumors. The approach is inspiring as it addresses both medical and surgical audiences. Score: 85 - 3 Stars" --Doody's

"In the last two decades, neuroscience research has made a big leap forward. The emergence of sophisticated genetic and molecular tools, combined with imaging techniques of unprecedented spatial and temporal resolution, and their application to in vivo models of major brain diseases allowed spectacular progress in our understanding of the structure and function of the brain in health and disease.

Furthering our knowledge of the nervous system generates both opportunities and responsibilities for the neuroscience community: opportunities to shed more light on the pathogenic mechanisms of neurological and psychiatric diseases, and responsibilities to use this knowledge for new therapeutic strategies that will benefit patients and society at large. There is no way to escape from the fact that brain disorders are a major public health problem in Europe and the rest of the world. Data collected by the World Health Organisation in 2004 show that brain diseases are responsible for 35% of Europe's total disease burden. Currently, the major disorders of central nervous system affect one in three people in the developed world, and brain diseases are among the most prevalent and debilitating diseases. Because most of these disorders are chronic, the individual's quality of life and socio-economic prospect are dramatically impaired. In addition, an analysis of the health economic studies of brain diseases in Europe, published by EBC in 2011 led to an estimate of ?798 billion for the total cost of brain disease in Europe in 2010. What is needed to face, what is becoming a societal emergency, is to strengthen research and develop a strong European platform for both basic and clinical brain research. Epilepsy is listed among the most costly brain diseases for the European society, accounting for a annual cost of 13.8 billion euros. Epilepsy caused by tumors needs a particular attention since it merges two major disabilitating diseases, thus representing a major clinical, economical, societal and ethical challenge. Addressing the large costs for the European society for this particular disease, requires intensified inter-disciplinar and multisectoral research and the creation of novel solutions. Volumes like Epilepsy and Brain Tumors will fill a gap in the scientific literature and give the much needed visibility to this challenging pathology." --Prof. Monica DiLuca, FENS President, University of Milan