Epilepsy (eBook, PDF)

Scientific Foundations of Clinical Practice
Redaktion: Rho, Jong M.; Cavazos, Jose E.; Sankar, Raman

• Format: PDF

Produktbeschreibung

The most up-to-date reference on the topic, Epilepsy analyzes the most relevant research developments in parallel clinical issues impacting modern therapeutic regimens-defining the scientific basis of current clinical practices and posing a set of challenging questions and considerations that may impact the future of clinical epilepsy research and investigation.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 532
• Erscheinungstermin: 23. April 2004
• Englisch
• ISBN-13: 9781135539375
• Artikelnr.: 55264212

Autorenporträt

Jong M. Rho, Unibersity of California at Irvine College of Medicne,USA. Raman Sankar, University of California. Los Angeles, US. Jose E. Cavazos, University of Texas Health Center at San Antonio, USA.

Inhaltsangabe

1. Introduction Part I: Scientific Foundations 2. Pathophysiology of
Seizures and Epilepsy 3. Drug Resistance in Epilepsy and Status Epilepticus
4. Genetics of Human Epilepsy-Epilepsy as a Channelopathy Part II:
Antiepileptic Drugs 5. Ontogeny of Molecular Targets of Antiepileptic
Drugs: Impact on Drug Choice 6. Epilepsy and Disease Modification: Animal
Models for Novel Drug Discovery 7. Nonsynaptic Mechanisms in Seizures and
Epileptogenesis: Targets for Clinical Management? 8. A Mechanistic Approach
to Antiepileptic Drug Interactions 9. Toxicology of Idiosyncratic Organ
Toxicities of AEDs Part III: Epilepsy Surgery 10. Advances in Structural
and Functional Neuroimaging: How Are These Guiding Epilepsy Surgery? 11.
Magnetoencephalography in Clinical Epilepsy 12. Nonsurgical Ablation of
Epileptic Tissue Part IV: Alternative Therapies 13. Special Treatments in
Epilepsy 14. The Ketogenic Diet: Scientific Principles Underlying Its Use
15. Vagus Nerve Stimulation 16. Immunomodulation of Epilepsy 17
Neurosteroids: Endogenous Modulators of Seizure Susceptibility Part V:
Other Modulators of the Epileptic State 18. Impact of Neuroendocrine
Factors on Seizure Genesis and Treatment 19. Chronobiology and Sleep:
Implications for Seizure Propensity 20. Psychopathology in Epilepsy: A
Window to Brain Behavior Relationships Part VI: The Future of Epilepsy
Therapy 21. Novel Mechanisms of Drug Delivery 22. Deep Brain Stimulation:
Why Should This Work? 23. Intraoperative Optical Imaging of Epileptiform
and Functional Activity 24. Early Seizure Detection: Theoretical and
Applied 25. Arresting Epileptogenesis: The Current Challenge