Epithelial Transport Physiology (eBook, PDF)

Redaktion: Gerencser, George A.

• Format: PDF

Produktbeschreibung

The general theme of Epithelial Transport Physiology is epithelial transport of molecules and ions, which includes the regulation of these mechanisms either directly, through secondary messengers, or via nuclear commands. Biologic transport of ions and, or, molecules across epithelial bio-membranes are mediated by proteins or protein-based molecules. Over the past forty to forty-five years, the primary structures of many of these proteins have been elucidated. One of the universalities that has emerged during this investigative process is the commonality of function amongst epithelial transporters up and down the phylogenetic tree of animals. The central subject of Epithelial Transport Physiology is to provide a comprehensive, contemporary review of epithelial transport and the responsible transporter proteins, while elucidating the wide spectrum of new methods examining epithelial transporters such as patch clamping, reconstitution, molecular biology and molecular physiology that are now available for the application to epithelial plasma membrane systems.

Contributors to this volume were chosen by the editor, George A. Gerencser, and were selected for their outstanding accomplishments in the field, and for their clarity and breadth of presentation. Epithelial Transport Physiology is directed to both basic and clinical scientists working in membrane transport and related areas, to graduate students and advanced undergraduates seeking a broad purview of the subject, and to other investigators and potential investigators seeking a vista of the new frontiers of molecular epithelial transporters.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 488
• Erscheinungstermin: 10. März 2010
• Englisch
• ISBN-13: 9781603272292
• Artikelnr.: 37343172

Inhaltsangabe

Chloride ATPase Pumps in Epithelia.- Divalent Anion Transport in Crustacean and Molluscan Gastrointestinal Epithelia.- Heavy Metal Transport and Detoxification by Crustacean Epithelial Lysosomes.- Epithelial Calcium Transport in Crustaceans: Adaptation to Intrinsic and Extrinsic Stressors.- The Cellular Basis of Extreme Alkali Secretion in Insects: A Tale of Two Tissues.- H+, Na+, K+, and Amino Acid Transport in Caterpillar and Larval Mosquito Alimentary Canal.- CFTR-Dependent Anion Transport in Airway Epithelia.- Sulfate and Phosphate Transporters in Mammalian Renal and Gastrointestinal Systems.- Role of H+-K+ ATPase, Na+-K+-2Cl? and Na+-Cl?-HCO3 ? Transporters in Vertebrate Small Intestine.- The H+- and H+, K+-ATPases of the Collecting Duct.- Acid/Base Regulation in Renal Epithelia by H,K-ATPases.- Sodium Transport Mechanisms in the Mammalian Nephron.- Renal Acid-Base Regulation Via Ammonia Transport in Mammals.- Hexose Transport Across Mammalian Epithelia.- Amino Acid Transport by Epithelial Membranes.- Molecular Ontology of Amino Acid Transport.

Rezensionen

From the reviews:

"Gerencser calls attention to the universality of transport protein functions across invertebrate and vertebrate taxa in Epithelial Transport Physiology. ... this volume will be a resource for researchers who require working knowledge of the transporters and processes that have been covered. This textbook has the potential to enhance graduate-level classes with permissively extensive curricula. Without doubt, the transcendental view of transport physiology that Gerencser has presented will appeal to the curiosity of erudite physiologists and this volume will be a valuable addition to their collections." (Jason R. Rock, The Quarterly Review of Biology, Vol. 86 (4), December, 2011)