This book is a collection of the major publications of the authors in the emerging area of chemotherapeutic engineering. It describes and demonstrates the concept, feasibility, safety and prospect of chemotherapeutic engineering through a full spectrum of proof-of-concept experiments. The range of coverage includes design, characterization, in vitro cellular uptake, cytotoxicity, and in vivo pharmacokinetics. The book also examines biodistribution and xenograft tumor modeling of the various nanocarriers, such as prodrugs, micelles, liposomes, and nanoparticles of biodegradable polymers.
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