Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods.
- Written by leaders in the field of clinical research who have published extensively with authorship of hundreds of articles in medical journals.
- The authorship includes one of the three authors of the CONSORT guidelines for the reporting of randomized controlled trials.
- The book presents the essential concepts to a wide array of topics including randomized control trials, descriptive studies, cohort studies, case-control studies, bias, and screening tests.
- The book utilises a readable and humorous prose style, lightening what can be a difficult area for clinical readers.
- Derived from decades of teaching clinical research in seminar settings the book will empower clinicians to make sense of, and critically appraise, current medical research and will enable researchers to enrich the quality of their work.
The updated new edition includes six new chapters:
- Surrogate endpoints
- Limitations of observational epidemiology
- Participant recruitment
- Practicalities of double-blinding
- Randomized trials in the context of a prospective meta-analysis
- Reporting studies in medical journals: CONSORT
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