Kingsley Adimabua, G. A. Awemu, C. A. Okonkwo, A. M. Odiegwu

Evaluation of the Wound Healing Effect of Herbal Ointment Formulated with "Crateva Religiosa" Leaf Extract (eBook, PDF)

• Format: PDF

Produktbeschreibung

Research Paper (postgraduate) from the year 2013 in the subject Medicine - Pharmacology, Madonna University Elele, Nigeria, course: Pharmaceutical and Medicinal Chemistry, language: English, abstract: The leaves of Crateva religiosa are used in traditional medicine for the treatment of various kinds of wounds. The present study was undertaken to evaluate the effect of herbal ointments formulated with the methanol extract of Crateva religiosa leaf on experimentally induced wounds in rats using the excision wound model. The animals were divided into five groups of five animals each. In the test groups 10, 15 and 20% extract of C. religiosa were topically applied once a day as ointment on groups 2, 3 and 4, respectively. Group 1 received blank petroleum jelly topically once a day while group 5 was treated topically with the standard drug, penicillin ointment. The mean wound sizes of all the animals were measured on the 3rd, 9th, 15th and 18th day post wounding and the mean percentage reduction in wound area calculated. Results obtained showed a dose dependent percentage reduction in wound area with the the 15% C. religiosa leaf extract (group 3) recording the highest mean percentage wound reduction (83 %) compared to the standard drug penicillin ointment which achieved complete wound healing after 18 days post wounding. This study suggests that C. religiosa leaf extract could be developed as a therapeutic agent for wound healing.

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Produktdetails

• Verlag: GRIN Verlag
• Seitenzahl: 5
• Erscheinungstermin: 5. Februar 2013
• Englisch
• ISBN-13: 9783656367291
• Artikelnr.: 37547531

Autorenporträt

Biography of Kingsley Adimabua: Kingsley Adimabua is a dedicated and experienced Humanitarian and Development worker hailing from Abuja, Nigeria. With a career spanning 11 years, Kingsley has made significant contributions to various esteemed organizations within the field. His passion for making a positive impact on communities and his expertise in Monitoring and Evaluation (M&E) and Information and Knowledge Management have set him apart as a strong candidate. Throughout his professional journey, Kingsley has had the privilege of working with reputable organizations such as Malaria Consortium, Christian Aid, Cuso International, Save the Children, Oxfam Novib, eHealth Africa, CBM International, and Palladium in Nigeria. His notable achievements include establishing a harmonized Post Distribution Monitoring system for a consortium of organizations involved in the Nigerian Joint Humanitarian Response and implementing effective Information and Knowledge management systems for Oxfam