Evidence Based Pathology and Laboratory Medicine (eBook, PDF)

Redaktion: Marchevsky, Alberto M.; Wick, Mark

• Format: PDF

Produktbeschreibung

Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "hard data" to support therapeutic and diagnostic modalities.

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 361
• Erscheinungstermin: 1. Juli 2011
• Englisch
• ISBN-13: 9781441910301
• Artikelnr.: 43792101

Inhaltsangabe

Introduction to Evidence-Based Pathology and Laboratory Medicine.- Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty.- What Is Best Evidence in Pathology?- Biostatistics 101.-Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative Model.- Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem Cases.- Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study Results.- Power Analysis and Sample Sizes in Pathology Research.- Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies.- Decision Analysis and Decision Support Systems in Anatomic Pathology.- Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience.- Evidence-Based Cell Pathology Re-visited: A Personal View.- Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical Center.- Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based Approach.- Metaanalysis 101 for Pathologists.- Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-Purposes.- Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into Practice.- The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory Evidence.- Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support Systems.- Evidence-Based Pathology and Tort Law: How Do They Compare?-. Index.

Rezensionen

From the reviews:

"This is the first edition of a book on the modern topic of 'Evidence Based Pathology and Laboratory Medicine'. ... it seems to be targeting US clinical pathology residents or graduates with experience and interest in both fields. ... the book gives a well-described view of the definition, application and predicted future of this rather young field in laboratory medicine." (Mehdi Mirzazadeh, Annals of Clinical Biochemistry, Vol. 49 (5), September, 2012)

"The purpose is to introduce evidence-based medicine principles and their application to the practice of pathology. ... the book would be useful for medical students or residents early in their pathology residency training. It also would be useful to practicing pathologists who are interested in evidence-based medicine and its application to everyday pathology practice. ... This is a provocative book useful for readers relatively unfamiliar with evidence-based medicine and interested in its application to anatomic pathology practice." (Valerie L. Ng, Doody's Book Reviews, September, 2011)

"The book, both coauthored in part and edited fully by two eminent professors of Pathology in the United States, comprises 361 pages, organized into 2 principal sections and divided evenly into 20 multiauthored, well-written and well-structured chapters. ... specialists engaged in clinical pathology and laboratory medicine will find this monograph an excellent source of information and worthy of review ... . a valuable and highly readable resource for those practitioners who recognize the inevitability of new and stimulating challenges in clinical pathology and laboratory medicine." (Claas T. Buschmann, Forensic Science, Medicine and Pathology, September, 2011)