Evolution of the Protein Synthesis Machinery and Its Regulation (eBook, PDF)

Redaktion: Hernández, Greco; Jagus, Rosemary

• Format: PDF

Produktbeschreibung

The "omics" era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

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Produktdetails

• Verlag: Springer Nature Switzerland
• Seitenzahl: 564
• Erscheinungstermin: 10. August 2016
• Englisch
• ISBN-13: 9783319394688
• Artikelnr.: 46924818

Autorenporträt

Greco Hernández, PhD. Division of Basic Research National Institute for Cancer (INCan) 22 San Fernando Ave. Tlalpan. 14080 Mexico City, Mexico Phone: [phone] Fax: [phone] Email: [e-mail] Rosemary Jagus Institute of Marine and Environmental Technology University of Maryland Center for Environmental Science 701 E. Pratt Street Baltimore MD 21202, U.S. Email: [e-mail]

Inhaltsangabe

A review on the origin of the different codes for translation.- Evolution of ribosomes.- Origins and early evolution of ribosomes.- Evolution of ribosomes and ribosomal proteins.- Evolution of Class II aminoacyl synthetases from the antisense of the genes for Class I.- The translation process during the evolutionary transition from prokaryotes to eukaryotes.- Evolution of translational control: from archaea to eukarya.- Distribution of elongation family GTPases EF1A and EFL in basal alveolate lineages.- Evolution of mRNA structure; the eukaryotic mRNA 5´- and 3´- untranslated regions and their role in translational regulation.- How lower eukaryotes contribute on our understanding of eIF4E-dependent translation.- Evolution of functionally divergent eIF4Es and their roles in the regulation of mRNA recruitment and developmental processes.- Evolution of eIF4E and eIF4G interactions in trypanosomes.- Evolution of the functionally divergent eIF4E family members in deuterostomes.- Evolution of the eIF2alpha kinases and translational control.- Evolution and use of eIF2alpha kinases in the apicomplexans and their role in life history of the parasites Plasmodium falciparum and Toxoplasma gondii.- Evolution of the TOR pathway and translational regulation.- Origin and diversification of eIF4E-binding proteins.- Evolution of the protein synthesis machinery in mitochondria.- Relationship between plant translation initiation factors and RNA viruses: An evolutionary perspective.- Evolution of miRNAs and RNA binding proteins in eukaryotes.- Evolution of silencing foci across eukaryotes.- Evolutionary conservation of the machineries coupling RNA transport with translation in eukaryotes.