Gustavo Caetano-Anollés

Evolutionary Genomics and Systems Biology (eBook, PDF)

• Format: PDF

Produktbeschreibung

A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams--macromolecular components in interaction--in the context of genomic complements. The book also features: * A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology * A special section on RNA biology--translation, evolution of structure, and micro RNA and regulation of gene expression * Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease * Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 480
• Erscheinungstermin: 12. Juli 2010
• Englisch
• ISBN-13: 9780470570401
• Artikelnr.: 37297166

Autorenporträt

Gustavo Caetano-Anollés, PhD, is Professor in the Department of Crop Sciences at the University of Illinois in Urbana-Champaign, Illinois. He has more than 150 well-cited original research publications in areas related to DNA technology and genomics, and holds half a dozen US patents in various areas of DNA science and biotechnology. His successful book, DNA Markers: Protocols, Applications, and Overviews, was published by Wiley in 1997.

Inhaltsangabe

Preface. Contributors. Part I. Evolution of Life. 1. Evolutionary Genomics
Leads the Way (David Penny and Lesley J. Collins). 2. Current Approaches to
Phylogenomic Reconstruction (Denis Baurain and Hervé Philippe). 3. The
Universal Tree of Life and the Last Universal Cellular Ancestor: Revolution
and Counterrevolutions (Patrick Forterre). 4. Eukaryote Evolutions: The
Importance of the Stem Group (Anthony M. Poole). 5. The Role of Information
in Evolutionary Genomics of Bacteria (Antoine Danchin and Agnieszka
Sekowska). 6. Evolutionary Genomics of Yeasts (Bernard Dujon). Part II.
Evolution of Molecular Repertoires. 7. Genotypes and Phenotypes in the
Evolution of Molecules (Peter Schuster). 8. Genome Evolution Studies
Through Protein Structure (Philip E. Bourne, Kristine Briedis, Christopher
Dupont, Ruben Valas, and Song Yang). 9. Chromosomal Rearrangements in
Evolution (Hao Zhao and Guillaume Bourque). 10. Molecular Structure and
Evolution of Genomes (Todd A. Castoe, A. P. Jason de Koning, and David D.
Pollock). 11. The Evolution of Protein Material Costs (Jason G. Bragg and
Andreas Wagner). 12. Protein Domains as Evolutionary Units (Andrew D. Moore
and Erich Bornberg-Bauer). 13. Domain Family Analyses to Understand Protein
Function Evolution (Adam James Reid, Sarah Addou, Robert Rentzsch, Juan
Ranea, and Christine Orengo). 14. Noncoding RNA (Alexander Donath, Sven
Findei², Jana Hertle, Manja Marz, Wolfgang Otto, Christine Schulz, Peter F.
Stadler, and Stefan Wirth). 15. Evolutionary Genomics of microRNAs and
Their Relatives (Andrea Tanzer, Markus Reister, Jana Hertel, Clara Isabel
Bermudez-Santana, Jan Gorodkin, Ivo L. Hofacker, and Peter F. Stadler). 16.
Phylogenetic Utility of RNA Structure: Evolution's Arrow and Emergence of
Early Biochemistry and Diversified Life (Feng-Jie Sun, Ajith Harish, and
Gustavo Caetano-Anollés). Part III. Evolution of Biological Networks. 17. A
Hitchhiker's Guide to Evolving Networks (Charles G. Kurland and Otto G.
Berg). 18. Evolution of Metabolic Networks (Eivind Almaas). 19. Single-Gene
and Whole-Genome Duplications and the Evolution of Protein-Protein
Interaction Networks (Grigoris Amoutzias and Yves Van de Peer). 20.
Modularity and Dissipation in Evolution of Macromolecular Structures,
Functions, and Networks (Gustavo Caetano-Anollés, Liudmila Yafremava, and
Jay E. Mittenthal). Index.