Ex Vivo Engineering of the Tumor Microenvironment (eBook, PDF)

Redaktion: Aref, Amir R.; Barbie, David

• Format: PDF

Produktbeschreibung

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

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Produktdetails

• Verlag: Springer Nature Switzerland
• Seitenzahl: 135
• Erscheinungstermin: 9. Dezember 2016
• Englisch
• ISBN-13: 9783319453972
• Artikelnr.: 53033163

Autorenporträt

Amir R. Aref, PhD, is Instructor, Dana-Farber Cancer Institute, Harvard Medical School.

Inhaltsangabe

1.Introduction to Ex Vivo Cancer Models.- 2.Patient-derived Xenografts in Oncology.- 3.Organoid Culture: Applications in Development and Cancer.- 4.Microfluidics and future of cancer diagnostics.- 5.Advancing techniques and insights in circulating tumor cell (CTC) research.- 6.The Cancer Secretome.- 7.An overview of the tumor microenvironments and future of cancer therapy.