Drawn from nearly four decades of Lawrence L. Kupper's teaching experiences, this text presents theoretical statistical concepts, numerous exercises, and detailed solutions that span topics from basic probability to statistical inference. The text links theoretical principles to real-world situations, including some of the authors' own biostatistical work that has addressed complicated design and analysis issues in the health sciences. The authors explain the biostatistical principles needed to solve the exercises, which range in level of difficulty from fairly basic to more challenging. By working through these exercises, students develop a deep understanding of the principles of biostatistical theory.
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