Jixian Wang

Exposure-Response Modeling (eBook, PDF)

Methods and Practical Implementation

• Format: PDF

Produktbeschreibung

This book explores a wide range of topics in exposure-response modeling, from traditional PKPD modeling to other areas in drug development and beyond. It incorporates numerous examples and software programs for implementing novel methods. The book emphasizes dose adjustment and treatment adaptation based on dynamic exposure-response models, illustrates how to apply causal inference to exposure-response modeling in pharmacometrics and epidemiology, and links exposure-response modeling to clinical decision making through model-based decision analysis.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 351
• Erscheinungstermin: 17. Juli 2015
• Englisch
• ISBN-13: 9781466573215
• Artikelnr.: 43450726

Autorenporträt

Jixian Wang is a principal statistician at Celgene International, Switzerland. He worked on drug development for 14 years at GSK and Novartis Pharma and was an academic researcher at Edinburgh University and Dundee University, where he is still an honorary research fellow. His research interests include statistical methodology and its applications to real problems in pharmaceuticals, including exposure-safety, PKPD modeling, treatment/dose selection, health economics, benefit-risk and health technology assessments, and optimal trial design.