Familial Breast and Ovarian Cancer (eBook, PDF)

Genetics, Screening and Management
Redaktion: Morrison, Patrick J.

• Format: PDF

Produktbeschreibung

This publication surveys the profound and far-reaching ramifications that have arisen from the very significant advances in our understanding of the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, this book provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in the diagnosis, genetics, screening, prevention and management of familial breast cancer. This area has advanced in knowledge so rapidly that this publication provides an unrivalled source of information including sections on ethical and insurance issues and the different cultural differences in breast cancer. The use of recently devised cancer genetics clinics and different referral criteria and patterns to these clinics are detailed. The volume will be of immense value to all clinical geneticists, oncologists, and healthcare professionals involved in screening and counselling programmes.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 7. November 2002
• Englisch
• ISBN-13: 9780511057274
• Artikelnr.: 38192022

Autorenporträt

Consultant clinical geneticist with a special interest in cancer genetics, in the Northern Ireland Regional Genetics Service. Qualified MB BCh BAO in 1986 and MD in 1993 from Queens'' University Belfast. Held molecular biology and neurogenetics research fellowships from the Royal College of Physicians in Ireland from 1991-1994. Member of the UK Government''s Human Genetics Commission, World Federation of Neurology Research Group in Huntingdon Disease, a steering group member on the International Collaborative group on hereditary breast and ovarian cancer (ICG-HBOC) and a council member of the Irish Society of Human Genetics. Involved in many other genetics and cancer societies. Published over 100 peer-reviewed articles on all aspects of genetics, particularly late onset neurogenetics diseases, familial cancers and insurance isuues.

Inhaltsangabe

Part I. Molecular Biology and Natural History: 1. Introduction Patrick
Morrison, Shirley Hodgson and Neva Haites; 2. Overview of clinical genetics
of breast cancer Neva Haites and Helen Gregory; 3. Cowden syndrome and
related disorders Charis Eng; 4. Overview of clinical genetics of ovarian
cancer Pierre Chappuis and Will Foulkes; 5. Ovarian cancer as part of HNPCC
and other hereditary colon cancer syndromes Hans Vasen and M. A. Nooy; 6.
Natural history of hereditary breast cancer Dominique Stoppa-Lyonnet, Will
Foulkes and Pierre Chappuis; 7. Pathology of the breast and ovary in
mutation carriers Sunil Lakhani and Adrienne M. Flanagan; 8. Risk
estimation for familial breast and ovarian cancer Jenny Chang-Claude and
Heiko Becher; Part II. Screening: 9. Experience of setting up a cancer
genetics service Jonathon Gray; 10. Referral criteria for cancer genetics
clinics Diana Eccles; 11. Service aspects of cancer genetic clinics Neva
Haites and Shirley Hodgson; 12. Cultural and education aspects influencing
development of cancer genetics services in different European countries
Shirley Hodgson; 13. Screening, detection and survival patterns of breast
and other cancers in high risk families Pål Møller and Michael Steel; 14.
Screening for familial ovarian cancer Barnaby Rufford, Usha Menon and Ian
Jacobs; Part III. Management: 15. Management of BRCA 1/2 mutation carriers
Pierre Chappuis and Will Foulkes; 16. Management of ovarian cancer Dirk
Brinkman and Ian Jacobs; 17. Prophylactic mastectomy in mutation carriers
Gareth Evans, Fiona Lalloo and Andrew Balidam; 18. Psychosocial aspects of
genetic counselling Steven Sutton and Alison Bish; 19. BRCA 1 and 2
testing: uptake and its measurement Lucy Brooks and Gareth Evans; 20.
Ethical aspects Patrick Morrison and Michael Steel; 21. Gene therapy of
breast and ovarian cancer Richard Kennedy and Patrick Johnston; 22. Future
directions Patrick Morrison, Shirley Hodgson and Neva Haites.