S. Nayler, B. L. Rapoport, F. Schmitt, G. Troncone

Fast Facts: Comprehensive Genomic Profiling (eBook, ePUB)

Making precision medicine possible

• Format: ePub

Produktbeschreibung

Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy

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Produktdetails

• Verlag: Karger
• Seitenzahl: 108
• Erscheinungstermin: 3. November 2020
• Englisch
• ISBN-13: 9783318068191
• Artikelnr.: 61975348