Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders (eBook, PDF)

Redaktion: Lee, V. M. -Y.; Christen, Y.; Buee, L.; Trojanowski, J. Q.

• Format: PDF

Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 140
• Erscheinungstermin: 9. März 2013
• Englisch
• ISBN-13: 9783662040560
• Artikelnr.: 53394130

Inhaltsangabe

The Role of ?-Synuclein in Parkinson's Disease: A Biophysical Analogy to A? and Alzheimer's Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.