eBook, PDF

Fatty Acid and Lipotoxicity in Obesity and Diabetes (eBook, PDF)

Beschreibung

The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic beta cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and beta cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.

Technische Details

• Geräte: PC
• mit Kopierschutz
• Größe: 7.1MB

Barrierefreiheit

• Text-to-Speech

Autor

The Novartis Foundation is an international scientific and educational charity, which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research. Chairman: Bruce Spiegelman.

Produktdetails

• Verlag: John Wiley & Sons
• Erscheinungstermin: 2. August 2008
• Englisch
• ISBN-13: 9780470985564
• Artikelnr.: 37301141

Rezensionen

"This book will be an excellent resource for either beginning students or more established investigators in the field. The speakers are all top notch researchers who gave clear and informative presentations. The integrative nature of the follow up discussions and the excellent insights provided by the chair of the meeting throughout give the book an unusual coherence and consistency that is often lacking in broad, general reviews." ( Doody s , April 2008)