Karla Punkt

Fibre Types in Skeletal Muscles (eBook, PDF)

• Format: PDF

Produktbeschreibung

This book summarizes the present knowledge about skeletal muscle fibres. As an introduction the theoretical background of structure, contraction mechanism and development of muscle fibres is shortly described to understand the specific problems of different fibre types. The aim of the book is to characterize muscle fibre types from different points of view as we see it today. The intermingling of different classification systems has lead to some confusion in the literature about muscle fibre types. In the present book an overview about muscle fibre types is given, considering results from literature and own results. For the first time the metabolic fibre typing with cytophotometry has been performed. The cytophotometry as a tool in fibre typing is described in detail for practical use. Moreover, the metabolism and the adaptibility of a given fibre type under changing physiological and pathological conditions has been studied. Finally, the unusual muscle fibre types of extraocular muscles has been described. This book addresses researchers, physicians and students who are interested but not specialized in myology and who will be pleased to read only 100 pages instead of thousands of them.

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 112
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642593994
• Artikelnr.: 53087786

Inhaltsangabe

1 Introduction.- 1.1 General Remarks.- 1.2 Structure and Contraction Mechanism of Muscle Fibres.- 1.3 Intrafusal Fibres of Muscle Spindles.- 1.4 Satellite Cells.- 2 When Does Differentiation of Muscle Fibres Begin and Which Properties Characterize a Fibre Type? How Can the Muscle Fibre "Know" Whether to Be Fast or Slow, and Since When?.- 3 The Difficulties and Possibilities of Classifying Muscle Fibres in Distinct Nonoverlapping Types.- 4 Cytophotometry As a Tool in Fibre Typing.- 4.1 The Basic Principle.- 4.2 The Enzymes Which Are Useful for Cytophotometrical Fibre Typing.- 4.3 The Physiological-Metabolic Muscle Fibre Typing By Cytophotometry.- 4.4 The Reliability of Cytophotometrical Data.- 5 Changes of Muscle Fibre Properties Under Physiological and Pathological Conditions.- 5.1 Regional Differences.- 5.2 Development and Ageing.- 5.3 Hereditary Myopathy.- 5.4 Experimental Acute Hypoxia.- 5.5 Streptozotocin-Induced Diabetes.- 6 Fibre Type Transformation.- 6.1 Conclusions.- 7 FOG Fibres - The Most Adaptable Muscle Fibres.- 8 Are There Adaption Processes in -?-Motoneurons as in Muscle Fibres?.- 9 The Influence of the Muscle Type on the Properties of a Fibre Type.- 10 Correspondences Between Physiological-Metabolic Fibre Typing, ATPase-Fibre Typing and Differentiation of Myosin Isoforms.- 11 Expression of Nitric Oxide Synthase Isoforms and Protein Kinase-C? in the Different Fibre Types and Alterations by Diabetes and EGb 761 Pretreatment.- 11.1 Illustration of the Topic.- 11.2 Experimental Basis.- 11.3 The Correlation of NOSI, NOSIII and PKC? to the Fibre Types.- 11.4 The Effect of STZ-Induced Diabetes and EGb 761 on the Expression of NOSI and NOSIII in the Rat Vastus Lateralis Muscle.- 11.5 NOSII Expression in Skeletal Muscle Fibres.- 11.6 Conclusions.- 12Specific Muscle Fibre Types of Extraocular Muscles.- 12.1 The Complexity of Extraocular Muscles.- 12.2 Fibre Types of Extraocular Muscles.- 12.3 Summary.- 13 Summary.- 14 Conclusions.- References.