Fundamentals of Toxicologic Pathology (eBook, ePUB)

Redaktion: Wallig DVM; Rousseaux BVSc [Hons]; M Haschek BVSc; Bolon DVM

• Format: ePub

Produktbeschreibung

Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development.

The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.

• Presents revised and updated information for each chapter on systems
• Contains expanded sections on applied toxicologic pathology
• Includes the essential information necessary to understand toxicologic pathology in an accessible language

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 902
• Erscheinungstermin: 25. Oktober 2017
• Englisch
• ISBN-13: 9780128098424
• Artikelnr.: 49375206

Autorenporträt

Matthew A. Wallig, DVM, Ph.D., DACVP, is Professor Emeritus in the Department of Pathobiology, College of Veterinary Medicine, the Department of Food Science and Human Nutrition, as well as the Division of Nutritional Sciences at the University of Illinois. His research has focused on the chemoprotective properties and mechanisms of phytochemicals in the diet, in particular those in cruciferous vegetables, soy, and tomatoes. His current interests have expanded to include defining morphologic parameters for diagnostic quantitative ultrasound in pancreatitis, pancreatic and hepatic neoplasia, metastatic disease, and chronic hepatic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Matt has served as an Editor for the last two editions of the Fundamentals of Toxicologic Pathology and Haschek and Rousseaux's Handbook of Toxicologic Pathology.

Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology's Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA's FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology's Achievement Award in 2007 and the Midwest Regional Chapter - Society of Toxicology's Kenneth DuBois Award in 2011.

Inhaltsangabe

1. Overview of Toxicological Pathology

Part I: Principles of Toxicologic Pathology2. Biochemical and Molecular Basis of Toxicity3. Pharmacokinetics & Toxicokinetics 4. Principles of Pharmacodynamics & Toxicodynamics5. Morphologic Manifesations of Toxic Cell Injury6. Carcinogenesis: Mechanisms and Manifestation7. Design of Studies & Risk Management in Toxicologic Pathology

Part II: Systems Toxicologic Pathology8. Hepatobiliary System9. Cardiovascular System10. Muscular System11. Urinary System12. Immune System13. Hematopoietic System14. Respiratory Tract15. Digestive Tract16. Exocrine Pancreas17. Male Reproductive System18. Female Reproductive System19. Mammary Gland20. Endocrine System21. Nervous System22. Special Senses: Ocular Sytem22b. Special Senses: Auditory System23. Skeletal System (Bone & Joint)24. Integumentary System25. Embryo, Fetus & Placenta