Gene Regulation and Therapeutics for Cancer (eBook, PDF)

Redaktion: Batra, Surinder K.; Palanimuthu Ponnusamy, Moorthy

• Format: PDF

Produktbeschreibung

Advances in biotechnology have brought gene therapy to the forefront of medical research. This book focuses on specific gene regulation and therapeutics in various cancers and new technology used in the field, giving an overall picture to scientists and physicians who are working in cancer research.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 328
• Erscheinungstermin: 21. März 2021
• Englisch
• ISBN-13: 9781351778336
• Artikelnr.: 60803328

Autorenporträt

Surinder K. Batra is a Professor and Chairman of the Department of Biochemistry and Molecular Biology at the University of Nebraska Medical Center. Dr. Batra studies the functions of mucins in the progression of different malignancies. His recent studies demonstrated the molecular mechanism for the progression and metastasis of multiple cancers. His investigations led to developing several targeted therapies for different tumors. Based on his mechanistic and translational studies, different targets entered into Phase I/II trials for various cancers. Moorthy P. Ponnusamy is an Associate Professor of Biochemistry and Molecular Biology at the University of Nebraska Medical Centre. Dr. Ponnusamy's research background reflects a keen interest in understanding the molecular mechanisms of cancer stem cell-mediated progression and metastatis of pancreatic cancer. His recent studies discovered the specific mechanism for pancreatic cancer stem cell maintenance and its impact on metastatis. He is developing small molecules to target cancer stem cell populations.

Inhaltsangabe

Programmed Death 1 Receptor (PD-1)-mediated Immunomodulatory Effects in
Pancreatic Cancer. Nuclear Factor Kappa-B: Bridging Inflammation and
Cancer. The S100A7/8/9 Proteins: Novel Biomarker and Therapeutic Targets
for Solid Tumor Stroma. Nuclear Receptor Coactivators: Mechanism and
Therapeutic Targeting In Cancer. Liquid Biopsies for Pancreatic Cancer: A
Step Towards Early Detection. Targeting Subgroup-specific Cancer Epitopes
for Effective Treatment of Pediatric Medulloblastoma. Aberrant Methylation
of UC Promoters in Human Pancreatic Ductal Carcinomas. Receptor Tyrosine
Kinase Signaling Pathways as a Goldmine for Targeted Therapy in Head and
Neck Cancers. Molecular Drivers in Lung Adenocarcinoma: Therapeutic
Implications. Molecular Mediator of Prostate Cancer Progression and Its
Implication in Therapy. Therapeutic Options for Prostate Cancer: A
Contemporary Update. Regulation and Targeting of MUCINS in Pancreatic
Cancer. Targeted Therapy for Cancer Stem Cells.