Mauro Giacca

Gene Therapy (eBook, PDF)

• Format: PDF

Produktbeschreibung

This book presents to the reader a comprehensive and detailed, yet easily accessible, description of the whole field of gene therapy. It covers topics ranging from vector development to the results of the most recent clinical trials. It includes descriptions of lentiviral and AAV vector development, of therapeutic gene selection (including siRNAs, shRNAs, and microRNAs), and of the most recent clinical applications of gene therapy for diseases of the eye, the cardiovascular system, and the central nervous system. Of note, the book only considers conditions for which transfer of genetic material has already progressed to clinical applications or is close to doing so. The language is plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical fields, whenever technical descriptions are required these are provided. Readers will include graduate students in the life sciences area in their final years of study, PhD students, and medical doctors specializing in different fields of internal and specialist medicine, in addition to research scientists working in various areas of current biomedical research.

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Produktdetails

• Verlag: Springer Milan
• Seitenzahl: 303
• Erscheinungstermin: 1. November 2010
• Englisch
• ISBN-13: 9788847016439
• Artikelnr.: 43995255

Autorenporträt

Mauro Giacca, MD, PhD, is the Director of the Italian Component of the International Centre for Genetic Engineering and Biotechnology (ICGEB), an international research organisation based in Trieste, Italy, and full professor of molecular biology at the Faculty of Medicine of the University of Trieste. Over the last 20 years, he has participated in the front line in the development of the gene therapy field. He is internationally recognized as an expert in AAV vector biology and in the application of AAV vectors for the gene therapy of cardiovascular disorders.

Inhaltsangabe

to Gene Therapy.- Therapeutic Nucleic Acids.- Methods for Gene Delivery.- Clinical Applications of Gene Therapy.- Ethical and Social Problems of Gene Therapy.