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Inhaltsangabe
1: Methods of General Pharmacology.- 2: The Cell as a Physico-chemical System.- 3: General Characteristics of the Cell-Drug System.- 4: Reactions between Drugs and Active Proteins.- 5: The Action of Drugs on Catalysts and Enzymes.- 6: Action of Heavy Metals on Enzymes in vitro and in vivo.- 7: Action of Various Enzyme Poisons in vitro and in vivo.- 8: Concentration-action Relations I.- 9: Concentration-action Relations II.- 10: Quantitative Pharmacology and the Theory of Humoral Transmission.- 11: Kinetics of Drug Action.- 12: The Rate of Action of Drugs on Cells.- 13: Time-concentrations Curves.- 14: Individual Variation of Response to Drugs.- 15: Relation between Various Types of Curves Expressing Response of Cells to Drugs.- 16: Special Problems Relating to Variation of Populations.- 17: Quantitative Aspects of Drug Antagonism and of Drug Synergism.- 18: Qualitative Aspects of Drug Antagonism.- 19: Alternative Theories of Drug Action.- 20: Quantitative Aspects of Chemotherapy.- 21: Conclusion.- Index of Authors.- Index of Subjects.
1: Methods of General Pharmacology.- 2: The Cell as a Physico-chemical System.- 3: General Characteristics of the Cell-Drug System.- 4: Reactions between Drugs and Active Proteins.- 5: The Action of Drugs on Catalysts and Enzymes.- 6: Action of Heavy Metals on Enzymes in vitro and in vivo.- 7: Action of Various Enzyme Poisons in vitro and in vivo.- 8: Concentration-action Relations I.- 9: Concentration-action Relations II.- 10: Quantitative Pharmacology and the Theory of Humoral Transmission.- 11: Kinetics of Drug Action.- 12: The Rate of Action of Drugs on Cells.- 13: Time-concentrations Curves.- 14: Individual Variation of Response to Drugs.- 15: Relation between Various Types of Curves Expressing Response of Cells to Drugs.- 16: Special Problems Relating to Variation of Populations.- 17: Quantitative Aspects of Drug Antagonism and of Drug Synergism.- 18: Qualitative Aspects of Drug Antagonism.- 19: Alternative Theories of Drug Action.- 20: Quantitative Aspects of Chemotherapy.- 21: Conclusion.- Index of Authors.- Index of Subjects.
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